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Descriptor English: Chitinase-3-Like Protein 1
Descriptor Spanish: Proteína 1 Similar a Quitinasa-3
Descriptor proteína 1 similar a quitinasa 3
Entry term(s) glicoproteína 39 del cartílago
glucoproteína 39 del cartílago
proteína CGP-39
proteína CHI3L1
proteína GP-39
proteína YLK-40
Scope note: Lectina que une QUITINA pero carece de actividad quitinasa. Puede estar implicada en el remodelamiento tisular y en las respuestas celulares al medio ambiente, incluyendo la respuesta de los LINFOCITOS T COLABORADORES en la INFLAMACIÓN y en la sensibilización a alérgenos. Las mutaciones del gen CHI3L1 se asocian al ASMA.
Descriptor Portuguese: Proteína 1 Semelhante à Quitinase-3
Descriptor French: Protéine-1 similaire à la chitinase-3
Entry term(s): CGP 39 Protein
CGP-39 Protein
CHI3L1 Protein
Cartilage Glycoprotein 39
Chitinase 3 Like Protein 1
GP 39 Protein
GP-39 Protein
Glycoprotein 39, Cartilage
YLK 40 Protein
YLK-40 Protein
Tree number(s): D08.811.277.450.207.500
D12.776.503.070
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071451
Scope note: A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Adipokines (2003-2016)
Glycoproteins (1993-2016)
Lectins (2003-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56479
Unique ID: D000071451
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15
Chitinase-3-Like Protein 1 - Preferred
Concept UI M000614717
Scope note A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
Preferred term Chitinase-3-Like Protein 1
Entry term(s) CGP 39 Protein
CGP-39 Protein
CHI3L1 Protein
Cartilage Glycoprotein 39
Chitinase 3 Like Protein 1
GP 39 Protein
GP-39 Protein
Glycoprotein 39, Cartilage
YLK 40 Protein
YLK-40 Protein



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