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Descriptor English: Calnexin
Descriptor Spanish: Calnexina
Descriptor calnexina
Scope note: Lectina que se encuentra en las membranas del RETÍCULO ENDOPLÁSMICO que se une a OLIGOSACÁRIDOS por unión N específica que se encuentra en las proteínas recientemente sintetizadas. Puede desempeñar un papel en el PLEGAMIENTO DE PROTEÍNAS y degradación de proteínas mal plegadas en el retículo endoplásmico.
Descriptor Portuguese: Calnexina
Descriptor French: Calnexine
Entry term(s): IP90 Protein
Integral Membrane Protein IP90
Phosphoprotein pp90
pp90, Phosphoprotein
Tree number(s): D12.644.360.372.311
D12.776.157.125.412.311
D12.776.476.387.311
D12.776.503.295
D12.776.543.162
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D037281
Scope note: A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES found on newly synthesized proteins. It may play role in PROTEIN FOLDING or retention and degradation of misfolded proteins in the endoplasmic reticulum.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 139873-08-8
Previous Indexing: Calcium-Binding Proteins (1991-2002)
Public MeSH Note: 2003; CALNEXIN was indexed under CALCIUM-BINDING PROTEINS 1991-2002
History Note: 2003; use CALNEXIN (NM) 1991-2002
DeCS ID: 37385
Unique ID: D037281
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2017/06/30
Calnexin - Preferred
Concept UI M0193588
Scope note A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES found on newly synthesized proteins. It may play role in PROTEIN FOLDING or retention and degradation of misfolded proteins in the endoplasmic reticulum.
Preferred term Calnexin
Entry term(s) IP90 Protein
Integral Membrane Protein IP90
Phosphoprotein pp90
pp90, Phosphoprotein



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