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Descriptor English: Jagged-1 Protein
Descriptor Spanish: Proteína Jagged-1
Descriptor proteína jagged-1
Entry term(s) antígeno CD339
jagged-1
proteína del síndrome de Alagille
proteína jagged 1
proteína jagged1
proteína serrate 1
proteína serrate-1
proteína serrate1
Scope note: Proteína "serrate-jagged" (dentada) que actúa como ligando de los RECEPTORES NOTCH. Puede regular la DIFERENCIACIÓN CELULAR en la HEMATOPOYESIS y la ANGIOGÉNESIS FISIOLÓGICA. Las mutaciones del gen Jagged-1 se asocian al SÍNDROME DE ALAGILLE 1.
Descriptor Portuguese: Proteína Jagged-1
Descriptor French: Protéine jagged-1
Entry term(s): Alagille Syndrome Protein
Antigen, CD339
CD339 Antigen
Jagged 1
Jagged 1 Protein
Jagged-1
Jagged1 Protein
Serrate 1 Protein
Serrate-1 Protein
Serrate1 Protein
Tree number(s): D12.644.276.930.500
D12.776.157.125.797.500
D12.776.543.800.500
D23.529.930.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072100
Scope note: A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; JAGGED-1 PROTEIN was indexed under CALCIUM-BINDING PROTEINS; MEMBRANE PROTEINS; AND INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1991-2016
History Note: 2017 (1991)
DeCS ID: 56530
Unique ID: D000072100
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24
Jagged-1 Protein - Preferred
Concept UI M000616345
Scope note A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
Preferred term Jagged-1 Protein
Entry term(s) Alagille Syndrome Protein
Antigen, CD339
CD339 Antigen
Jagged 1
Jagged 1 Protein
Jagged-1
Jagged1 Protein
Serrate 1 Protein
Serrate-1 Protein
Serrate1 Protein



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