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Descriptor English: beta-Arrestins
Descriptor Spanish: beta-Arrestinas
Descriptor beta-arrestinas
Entry term(s) beta-arrestina
Scope note: Arrestinas no pertenecientes al sistema de la visión que regulan negativamente los RECEPTORES ACOPLADOS A PROTEÍNAS G (GPCRs) y que también pueden funcionar independientemente de la señalización por GPCR. Reclutan y unen a los GPCRs muchos factores de señalización diferentes entre los que están las PROTEÍNAS QUINASAS ACTIVADAS POR MITÓGENOS, la FAMILIA-SRC QUINASAS y la FILAMINAS. Pueden reconocer distintos estados de fosforilación de los receptores condicionando la especificidad de la respuesta celular a la señalización.
Descriptor Portuguese: beta-Arrestinas
Descriptor French: bêta-Arrestines
Entry term(s): beta Arrestin
beta Arrestins
beta-Arrestin
Tree number(s): D12.644.360.024.098.525
D12.776.157.057.005.525
D12.776.476.024.104.525
D12.776.543.090.525
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071557
Scope note: Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; BETA-ARRESTINS was indexed under ARRESTINS 1996-2016 and under ANTIGENS and EYE PROTEINS 1992-1996
History Note: 2017 (1992)
DeCS ID: 56532
Unique ID: D000071557
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/08/09
beta-Arrestins - Preferred
Concept UI M000615063
Scope note Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.
Preferred term beta-Arrestins
Entry term(s) beta Arrestin
beta Arrestins
beta-Arrestin



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