Search
Descriptor English: rhoC GTP-Binding Protein
Descriptor Spanish: Proteína rhoC de Unión a GTP
Descriptor proteína rhoC de unión a GTP
Entry term(s) miembro C de la familia de homólogos de ras
rhoC GTPasa
Scope note: Proteína rho que une GTP y que es prenilada (ver PRENILACIÓN DE PROTEÍNAS) en su C-terminal y que alterna entre el citoplasma y la membrana plasmática, conectando las vías de señalización del receptor con el ensamblado de las ADHESIONES FOCALES, FIBRAS DE ESTRÉS y la formación de anillos contráctiles durante la CITOCINESIS. Se sobreexpresa en las células tumorales en proliferación y en las metástasis.
Descriptor Portuguese: Proteína de Ligação a GTP rhoC
Descriptor French: Protéine rhoC liant le GTP
Entry term(s): GTP-Binding Protein, rhoC
ras Homolog Family Member C
rhoC GTP Binding Protein
rhoC GTPase
Tree number(s): D08.811.277.040.330.300.400.700.650
D12.776.157.325.515.700.650
D12.776.476.338.400.700.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075024
Scope note: A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.5.2
Previous Indexing: GTP-Binding Proteins (1991-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57001
Unique ID: D000075024
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22
rhoC GTP-Binding Protein - Preferred
Concept UI M000628896
Scope note A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.
Preferred term rhoC GTP-Binding Protein
Entry term(s) GTP-Binding Protein, rhoC
ras Homolog Family Member C
rhoC GTP Binding Protein
rhoC GTPase



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey