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Descriptor English: Apolipoprotein L1
Descriptor Spanish: Apolipoproteína L1
Descriptor apolipoproteína L1
Entry term(s) apolipoproteína L
proteína ApoL
proteína ApoL1
Scope note: Proteína apoL que se expresa ampliamente en el hígado. Tiene actividad antitripanosoma por su capacidad de permeabilizar las membranas del TRIPANOSOMA. Las mutaciones del gen APOL1 se asocian a GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA tipo 4.
Descriptor Portuguese: Apolipoproteína L1
Descriptor French: Apolipoprotéine L1
Entry term(s): ApoL Protein
ApoL1 Protein
Apolipoprotein L
Tree number(s): D10.532.091.750.500
D12.776.070.400.750.500
D12.776.521.120.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075944
Scope note: An ApoL protein highly expressed by the liver. It has anti-trypanosomal activity through its ability to permeabilize TRYPANOSOMA membranes. Mutations in the APOL1 gene are associated with type 4 FOCAL SEGMENTAL GLOMERULOSCLEROSIS .
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Apolipoproteins (1997-2017)
Lipoproteins, HDL (1997-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57041
Unique ID: D000075944
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/30
Apolipoprotein L1 - Preferred
Concept UI M000631728
Scope note An ApoL protein highly expressed by the liver. It has anti-trypanosomal activity through its ability to permeabilize TRYPANOSOMA membranes. Mutations in the APOL1 gene are associated with type 4 FOCAL SEGMENTAL GLOMERULOSCLEROSIS .
Preferred term Apolipoprotein L1
Entry term(s) ApoL Protein
ApoL1 Protein
Apolipoprotein L



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