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Descriptor English: Netrin-1
Descriptor Spanish: Netrina-1
Descriptor netrina-1
Entry term(s) proteína NTN1
proteína netrina-1
Scope note: Netrina que se une al RECEPTOR DCC o a receptores UNC5, lo que resulta, respectivamente, en atracción o repulsión del axón. Su interacción con estos receptores también previene la APOPTOSIS; también funciona como proteína supresora de tumores.
Descriptor Portuguese: Netrina-1
Descriptor French: Nétrine-1
Entry term(s): NTN1 Protein
Netrin 1
Netrin 1 Protein
Netrin-1 Protein
Protein, NTN1
Protein, Netrin-1
Tree number(s): D12.644.276.860.494.500
D12.776.467.860.494.500
D12.776.631.600.494.500
D12.776.860.300.731.500
D23.125.842.500
D23.529.850.494.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075388
Scope note: A netrin that binds the DCC RECEPTOR or UNC5 receptors, resulting respectively in axon attraction or repulsion. Its interaction with these receptors also prevents APOPTOSIS; it may function as a tumor suppressor protein.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 158651-98-0
Public MeSH Note: 2018; NETRIN-1 was indexed under NERVE GROWTH FACTORS 1994-2017; and under TUMOR SUPPRESSOR PROTEINS 2002-2017
History Note: 2018 (1994)
DeCS ID: 57055
Unique ID: D000075388
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22
Netrin-1 - Preferred
Concept UI M0235151
Scope note A netrin that binds the DCC RECEPTOR or UNC5 receptors, resulting respectively in axon attraction or repulsion. Its interaction with these receptors also prevents APOPTOSIS; it may function as a tumor suppressor protein.
Preferred term Netrin-1
Entry term(s) NTN1 Protein
Netrin 1
Netrin 1 Protein
Netrin-1 Protein
Protein, NTN1
Protein, Netrin-1



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