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Descriptor English: Vasopeptidase Inhibitors
Descriptor Spanish: Inhibidores de las Vasopeptidasas
Descriptor inhibidores de las vasopeptidasas
Entry term(s) inhibidor de las vasopeptidasas
inhibidores de ACE-NEP
inhibidores de ECA y EPN
inhibidores de NEP-ACE
Scope note: Clase de fármacos cardiovasculares indicados para la hipertensión y la insuficiencia cardíaca congestiva que inhiben tanto la NEPRILISINA (endopeptidasa neutra) como la ENZIMA CONVERTIDORA DE ANGIOTENSINA. Aumentan la disponibilidad de los PÉPTIDOS NATRIURÉTICOS y la BRADICININA e inhiben la producción de ANGIOTENSINA II.
Descriptor Portuguese: Inibidores de Vasopeptidases
Descriptor French: Inhibiteurs des vasopeptidases
Entry term(s): ACE NEP Inhibitors
ACE-NEP Inhibitors
NEP ACE Inhibitors
NEP-ACE Inhibitors
Vasopeptidase Inhibitor
Tree number(s): D27.505.519.389.745.085.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075563
Scope note: A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Angiotensin-Converting Enzyme Inhibitors (1999-2017)
Neprilysin/antagonists and inhibitors (1999-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57152
Unique ID: D000075563
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/07/07
Vasopeptidase Inhibitors - Preferred
Concept UI M000630678
Scope note A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.
Preferred term Vasopeptidase Inhibitors
Entry term(s) ACE NEP Inhibitors
ACE-NEP Inhibitors
NEP ACE Inhibitors
NEP-ACE Inhibitors
Vasopeptidase Inhibitor



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