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Descriptor English: Silybin
Descriptor Spanish: Silibina
Descriptor silibina
Entry term(s) 2,3 deshidrosilibina
2,3-deshidrosilibina
Alepa forte
Alepa-forte
Hepa Merz Sil
Hepa loges
Hepa-Merz Sil
Hepa-loges
HepaBesch
Hepar Pasc
Hepar-Pasc
Heparsyx
Heplant
Legalon Forte
Silibina A
Silibina B
Silibinin B
ardeyhepan
cefasilymarin
durasilymarin
lagosa
silibinina
silibinina A
Scope note: El componente activo principal de los flavonoides silimarínicos extraídos de semillas del CARDO LECHERO, Silybum marianum; se usa en el tratamiento de la HEPATITIS, la CIRROSIS HEPÁTICA y los TRASTORNOS HEPÁTICOS PROVOCADOS POR FÁRMACOS Y PRODUCTOS QUÍMICOS, y tiene actividad antineoplásica; las silibinas A y B son diastereómeros.
Descriptor Portuguese: Silibina
Descriptor French: Silibinine
Entry term(s): 2,3 Dehydrosilybin
2,3-Dehydrosilybin
Alepa forte
Alepa-forte
Ardeyhepan
Cefasilymarin
Durasilymarin
Hepa Merz Sil
Hepa loges
Hepa-Merz Sil
Hepa-loges
HepaBesch
Hepar Pasc
Hepar-Pasc
Heparsyx
Heplant
Lagosa
Legalon Forte
Silibin
Silibinin
Silibinin A
Silibinin B
Silybin A
Silybin B
Silybinin
Tree number(s): D03.383.663.283.266.450.268.777.500
D03.633.100.150.266.450.268.777.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077385
Scope note: The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Phytogenic
Protective Agents
Registry Number: 4RKY41TBTF
CAS Type 1 Name: 4H-1-Benzopyran-4-one, 2-((2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-
Public MeSH Note: 2019; SILYBIN was indexed under SILYMARIN 2002-2018
History Note: 2019 (2002)
DeCS ID: 57629
Unique ID: D000077385
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/07
Silybin - Preferred
Concept UI M0019880
Scope note The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers.
Preferred term Silybin
Entry term(s) Silibin
Silibinin
Silybinin
Ardeyhepan - Narrower
Concept UI M0475693
Preferred term Ardeyhepan
Cefasilymarin - Narrower
Concept UI M0475694
Preferred term Cefasilymarin
Durasilymarin - Narrower
Concept UI M0475695
Preferred term Durasilymarin
Hepa-loges - Narrower
Concept UI M0475696
Preferred term Hepa-loges
Entry term(s) Hepa loges
Hepa-Merz Sil - Narrower
Concept UI M0475697
Preferred term Hepa-Merz Sil
Entry term(s) Hepa Merz Sil
Silybin B - Narrower
Concept UI M000629762
Preferred term Silybin B
Entry term(s) Silibinin B
Alepa-forte - Narrower
Concept UI M0475692
Preferred term Alepa-forte
Entry term(s) Alepa forte
HepaBesch - Narrower
Concept UI M0475698
Preferred term HepaBesch
Hepar-Pasc - Narrower
Concept UI M0475699
Preferred term Hepar-Pasc
Entry term(s) Hepar Pasc
Heparsyx - Narrower
Concept UI M0475700
Preferred term Heparsyx
Lagosa - Narrower
Concept UI M0475703
Preferred term Lagosa
2,3-Dehydrosilybin - Narrower
Concept UI M0500595
Preferred term 2,3-Dehydrosilybin
Entry term(s) 2,3 Dehydrosilybin
Legalon Forte - Narrower
Concept UI M0554692
Preferred term Legalon Forte
Silybin A - Narrower
Concept UI M000629761
Preferred term Silybin A
Entry term(s) Silibinin A
Heplant - Narrower
Concept UI M0475702
Preferred term Heplant



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