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Descriptor English: Ivabradine
Descriptor Spanish: Ivabradina
Descriptor ivabradina
Entry term(s) 7,8-dimetoxi-3-(3-(((4,5-dimetoxibenzociclobutan-1-il)metil)metilamino)propil)-1,3,4,5-tetrahidro-2H-benzazepin-2-ona
S 16257
S 16257 2
S 16257-2
S 162572
S 16260 2
S 16260-2
S 162602
S-16257
S-16257-2
S-16260-2
S16257
S162572
S162602
corlanor
Scope note: Derivado benzacepínico e inhibidor selectivo de los CANALES REGULADOS POR NUCLEÓTIDOS CÍCLICOS ACTIVADOS POR HIPERPOLARIZACIÓN que reduce la frecuencia cardíaca. Se usa en el tratamiento de la ANGINA CRÓNICA ESTABLE en pacientes que no pueden tomar BLOQUEANTES DE LOS RECEPTORES ADRENÉRGICOS BETA y en el tratamiento de la INSUFICIENCIA CARDÍACA.
Descriptor Portuguese: Ivabradina
Descriptor French: Ivabradine
Entry term(s): 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
Corlanor
S 16257
S 16257 2
S 16257-2
S 162572
S 16260 2
S 16260-2
S 162602
S-16257
S-16257-2
S-16260-2
S16257
S162572
S162602
Tree number(s): D03.633.100.079.801
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077550
Scope note: A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Cardiovascular Agents
Registry Number: 3H48L0LPZQ
CAS Type 1 Name: 2H-3-Benzazepin-2-one, 3-(3-((((7S)-3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-
Public MeSH Note: 2019; IVABRADINE was indexed under BENZAZEPINES 1994-2018
History Note: 2019 (1994)
DeCS ID: 57675
Unique ID: D000077550
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/20
Ivabradine - Preferred
Concept UI M0234009
Scope note A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.
Preferred term Ivabradine
7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one - Narrower
Concept UI M000640894
Preferred term 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
S 16257 - Narrower
Concept UI M0234003
Preferred term S 16257
Entry term(s) S-16257
S16257
S 16257-2 - Narrower
Concept UI M0234004
Preferred term S 16257-2
Entry term(s) S 16257 2
S 162572
S 16260 2
S 16260-2
S 162602
S-16257-2
S-16260-2
S162572
S162602
Corlanor - Narrower
Concept UI M000605160
Preferred term Corlanor



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