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Descriptor English: Varenicline
Descriptor Spanish: Vareniclina
Descriptor Portuguese: Vareniclina
Descriptor French: Varénicline
Entry term(s): 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine
Champix
Chantix
Varenicline Tartrate
Tree number(s): D03.633.100.079.900
D03.633.100.857.942
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068580
Scope note: A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Smoking Cessation Agents
Nicotinic Agonists
Registry Number: W6HS99O8ZO
Public MeSH Note: 2016; VARENICLINE was indexed under BENZAZEPINES, 2005-2015 and under QUINOXALINES, 2005-2015
History Note: 2016 (2005)
DeCS ID: 55932
Unique ID: D000068580
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2018/06/19
Varenicline - Preferred
Concept UI M0485421
Scope note A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.
Preferred term Varenicline
Entry term(s) 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine
Chantix - Narrower
Concept UI M0497892
Preferred term Chantix
Varenicline Tartrate - Narrower
Concept UI M0540610
Preferred term Varenicline Tartrate
Champix - Narrower
Concept UI M0511350
Preferred term Champix



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