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Descriptor English: Edaravone
Descriptor Spanish: Edaravona
Descriptor edaravona
Entry term(s) 1 fenil 3-metil 5 pirazolona
1-fenil-3-metil-5-pirazolona
3-metil-1-fenil-2-pirazolin-5-ona
MCI 186
MCI-186
MCI186
Radicava
fenilmetilpirazolona
norantipirina
norfenazona
Scope note: Derivado de la fenazona (antipirina) que actúa como neutralizador de radicales libres y como neuroprotector. Se usa en el tratamiento de la ESCLEROSIS LATERAL AMIOTRÓFICA y del ACCIDENTE CEREBROVASCULAR.
Descriptor Portuguese: Edaravone
Descriptor French: Édaravone
Entry term(s): 1 Phenyl 3 methyl 5 pyrazolone
1-Phenyl-3-methyl-5-pyrazolone
3 Methyl 1 phenyl 2 pyrazolin 5 one
3-Methyl-1-phenyl-2-pyrazolin-5-one
Edarabone
MCI 186
MCI-186
MCI186
Norantipyrine
Norphenazone
Phenylmethylpyrazolone
Radicava
Tree number(s): D03.383.129.539.850.088.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077553
Scope note: An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Free Radical Scavengers
Neuroprotective Agents
Registry Number: S798V6YJRP
CAS Type 1 Name: 3H-pyrazol-3-one, 2,4-dihydro-5-methyl-2-phenyl-
Public MeSH Note: 2019; see PHENYLMETHYLPYRAZOLONE 1970-2018; EDARAVONE was indexed under ANTIPYRINE/analogs&derivatives 1982-2018; and under PYRAZOLES 1970-1981
History Note: 2019 (1970)
DeCS ID: 57678
Unique ID: D000077553
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Edaravone - Preferred
Concept UI M0046983
Scope note An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.
Preferred term Edaravone
Entry term(s) Edarabone
Norantipyrine
Norphenazone
1-Phenyl-3-methyl-5-pyrazolone - Broader
Concept UI M000640902
Preferred term 1-Phenyl-3-methyl-5-pyrazolone
Entry term(s) 1 Phenyl 3 methyl 5 pyrazolone
3 Methyl 1 phenyl 2 pyrazolin 5 one
3-Methyl-1-phenyl-2-pyrazolin-5-one
MCI 186 - Narrower
Concept UI M0046979
Preferred term MCI 186
Entry term(s) MCI-186
MCI186
Radicava - Narrower
Concept UI M000631346
Preferred term Radicava
Phenylmethylpyrazolone - Broader
Concept UI M000640901
Preferred term Phenylmethylpyrazolone



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