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Descriptor English: Icodextrin
Descriptor Spanish: Icodextrina
Descriptor Portuguese: Icodextrina
Descriptor French: Icodextrine
Entry term(s): Extraneal
Icodial
Tree number(s): D05.750.078.562.622
D09.698.365.399
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077607
Scope note: A glucan that is structurally related to maltodextrin, with more than 85% of its molecules having molecular weights between 1640 and 45 000 Daltons (Da), and a weight-average molecular weight of about 20 000 Da; it is used in dialysis fluids as an alternative to glucose-based solutions, and to reduce adhesions after gynecological or abdominal surgery. It has also been used as a vehicle for drugs given via the peritoneal cavity.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Dialysis Solutions
Registry Number: 2NX48Z0A9G
Public MeSH Note: 2019; ICODEXTRIN was indexed under GLUCANS and GLUCOSE 1997-2018
History Note: 2019 (1997)
DeCS ID: 57710
Unique ID: D000077607
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Icodextrin - Preferred
Concept UI M0275943
Scope note A glucan that is structurally related to maltodextrin, with more than 85% of its molecules having molecular weights between 1640 and 45 000 Daltons (Da), and a weight-average molecular weight of about 20 000 Da; it is used in dialysis fluids as an alternative to glucose-based solutions, and to reduce adhesions after gynecological or abdominal surgery. It has also been used as a vehicle for drugs given via the peritoneal cavity.
Preferred term Icodextrin
Extraneal - Narrower
Concept UI M0446679
Preferred term Extraneal
Icodial - Narrower
Concept UI M0446680
Preferred term Icodial



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