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Descriptor English: Bexarotene
Descriptor Spanish: Bexaroteno
Descriptor bexaroteno
Entry term(s) 3-metil-TTNEB
LGD 1069
LGD-1069
LGD1069
Targretin
compuesto LG69
ácido 4-(1-(3,5,5,8,8-pentametil-5,6,7,8-tetrahidro-2-naftil)etenil)benzoico
Scope note: Rexinoide (ligando de unión al RXR), derivado del tetrahidronaftaleno y antagonista del RECEPTOR DEL RETINOIDE X que se usa en el tratamiento del LINFOMA CUTÁNEO DE CÉLULAS T.
Descriptor Portuguese: Bexaroteno
Descriptor French: Bexarotène
Entry term(s): 3-methyl-TTNEB
4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid
LG69 compound
LGD 1069
LGD-1069
LGD1069
Targretin
Tree number(s): D02.455.426.559.847.638.960.423
D04.615.638.960.423
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077610
Scope note: A rexinoid (an RXR-binding ligand), tetrahydronaphthalene derivative and RETINOID X RECEPTOR antagonist that is used in the treatment of CUTANEOUS T-CELL LYMPHOMA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Antineoplásicos
Antineoplásicos
Antinéoplasiques
antineoplásicos
Registry Number: A61RXM4375
Public MeSH Note: 2019; BEXAROTENE was indexed under TETRAHYDRONAPHTHALENES 1995-2018
History Note: 2019 (1995)
DeCS ID: 57713
Unique ID: D000077610
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2020/06/09
Bexarotene - Preferred
Concept UI M0250478
Scope note A rexinoid (an RXR-binding ligand), tetrahydronaphthalene derivative and RETINOID X RECEPTOR antagonist that is used in the treatment of CUTANEOUS T-CELL LYMPHOMA.
Preferred term Bexarotene
Entry term(s) 3-methyl-TTNEB
4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid
LG69 compound - Narrower
Concept UI M0250479
Preferred term LG69 compound
LGD 1069 - Narrower
Concept UI M0250483
Preferred term LGD 1069
Entry term(s) LGD-1069
LGD1069
Targretin - Narrower
Concept UI M0250482
Preferred term Targretin



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