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Descriptor English: Tigecycline
Descriptor Spanish: Tigeciclina
Descriptor tigeciclina
Entry term(s) 9-(tert-butilglicilamido)minociclina
GAR 936
GAR-936
GAR936
TBG-MINO
Tygacil
Scope note: Derivado tetraciclínico que actúa como inhibidor de la síntesis de proteínas. Se usa como antibacteriano para el tratamiento sistémico de las infecciones cutáneas e intraabdominales complicadas. Se usa también para el tratamiento de la neumonía adquirida en la comunidad.
Descriptor Portuguese: Tigeciclina
Descriptor French: Tigecycline
Entry term(s): 9-(tert-Butylglycylamido)minocycline
GAR 936
GAR-936
GAR936
TBG-MINO
Tygacil
Tree number(s): D02.455.426.559.847.562.900.937
D04.615.562.900.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078304
Scope note: A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Antibacterianos
Antibacterianos
Antibactériens
antibacterianos
Protein Synthesis Inhibitors
Inhibidores de la Síntesis de la Proteína
Inibidores da Síntese de Proteínas
Inhibiteurs de la synthèse protéique
inhibidores de la síntesis proteica
Registry Number: 70JE2N95KR
CAS Type 1 Name: 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-((2-((1,1-dimethylethyl)amino)acetyl)amino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
Public MeSH Note: 2019; TIGECYCLINE was indexed under MINOCYCLINE/analogs & derivatives 1999-2018
History Note: 2019 (1999)
DeCS ID: 57796
Unique ID: D000078304
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19
Tigecycline - Preferred
Concept UI M0305009
Scope note A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia.
Preferred term Tigecycline
Entry term(s) 9-(tert-Butylglycylamido)minocycline
TBG-MINO
Tygacil - Narrower
Concept UI M0489861
Preferred term Tygacil
GAR 936 - Narrower
Concept UI M0490506
Preferred term GAR 936
Entry term(s) GAR-936
GAR936



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