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Descriptor English: Tigecycline
Descriptor Spanish: Tigeciclina
Descriptor tigeciclina
Entry term(s) 9-(tert-butilglicilamido)minociclina
GAR 936
GAR-936
GAR936
TBG-MINO
Tygacil
Scope note: Derivado tetraciclínico que actúa como inhibidor de la síntesis de proteínas. Se usa como antibacteriano para el tratamiento sistémico de las infecciones cutáneas e intraabdominales complicadas. Se usa también para el tratamiento de la neumonía adquirida en la comunidad.
Descriptor Portuguese: Tigeciclina
Descriptor French: Tigecycline
Entry term(s): 9-(tert-Butylglycylamido)minocycline
GAR 936
GAR-936
GAR936
TBG-MINO
Tygacil
Tree number(s): D02.455.426.559.847.562.900.937
D04.615.562.900.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078304
Scope note: A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Protein Synthesis Inhibitors
Registry Number: 70JE2N95KR
CAS Type 1 Name: 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-((2-((1,1-dimethylethyl)amino)acetyl)amino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
Public MeSH Note: 2019; TIGECYCLINE was indexed under MINOCYCLINE/analogs & derivatives 1999-2018
History Note: 2019 (1999)
DeCS ID: 57796
Unique ID: D000078304
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19
Tigecycline - Preferred
Concept UI M0305009
Scope note A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia.
Preferred term Tigecycline
Entry term(s) 9-(tert-Butylglycylamido)minocycline
TBG-MINO
Tygacil - Narrower
Concept UI M0489861
Preferred term Tygacil
GAR 936 - Narrower
Concept UI M0490506
Preferred term GAR 936
Entry term(s) GAR-936
GAR936



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