Descriptor English: | Tigecycline | ||||||
Descriptor Spanish: |
Tigeciclina
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Descriptor Portuguese: | Tigeciclina | ||||||
Descriptor French: | Tigecycline | ||||||
Entry term(s): |
9-(tert-Butylglycylamido)minocycline GAR 936 GAR-936 GAR936 TBG-MINO Tygacil |
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Tree number(s): |
D02.455.426.559.847.562.900.937 D04.615.562.900.937 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000078304 | ||||||
Scope note: | A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Anti-Bacterial Agents Antibacterianos Antibacterianos Antibactériens antibacterianos Protein Synthesis Inhibitors Inhibidores de la Síntesis de la Proteína Inibidores da Síntese de Proteínas Inhibiteurs de la synthèse protéique inhibidores de la síntesis proteica |
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Registry Number: | 70JE2N95KR | ||||||
CAS Type 1 Name: | 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-((2-((1,1-dimethylethyl)amino)acetyl)amino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)- | ||||||
Public MeSH Note: | 2019; TIGECYCLINE was indexed under MINOCYCLINE/analogs & derivatives 1999-2018 |
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History Note: | 2019 (1999) |
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DeCS ID: | 57796 | ||||||
Unique ID: | D000078304 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2019/01/01 | ||||||
Date of Entry: | 2018/07/09 | ||||||
Revision Date: | 2018/06/19 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Polycyclic Compounds [D04]Polycyclic Compounds
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Tigecycline
- Preferred
Tygacil
- Narrower
GAR 936
- Narrower
Concept UI |
M0305009 |
Scope note | A tetracycline derivative that acts as a protein synthesis inhibitor. It is used as an antibacterial agent for the systemic treatment of complicated skin and intra-abdominal infections. It is also used for the treatment of community-acquired pneumonia. |
Preferred term | Tigecycline |
Entry term(s) |
9-(tert-Butylglycylamido)minocycline TBG-MINO |
Concept UI |
M0489861 |
Preferred term | Tygacil |
Concept UI |
M0490506 |
Preferred term | GAR 936 |
Entry term(s) |
GAR-936 GAR936 |
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