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Descriptor English: Methacycline
Descriptor Spanish: Metaciclina
Descriptor metaciclina
Scope note: Antibiótico semisintético de amplio espectro relacionado con la TETRACICLINA pero que se excreta más lentamente y y mantiene unas concentraciones hemáticas efectivas durante un mayor período de tiempo.
Descriptor Portuguese: Metaciclina
Descriptor French: Métacycline
Entry term(s): Lysocline
Metacycline
Methacycline Monohydrochloride
Methyleneoxytetracycline
Monohydrochloride, Methacycline
Physiomycine
Rondomycin
Tree number(s): D02.455.426.559.847.562.900.525
D04.615.562.900.525
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008690
Scope note: A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Registry Number: IR235I7C5P
CAS Type 1 Name: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-
Public MeSH Note: 68
History Note: 68(65)
DeCS ID: 8865
Unique ID: D008690
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Methacycline - Preferred
Concept UI M0013539
Scope note A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
Preferred term Methacycline
Entry term(s) Metacycline
Methyleneoxytetracycline
Rondomycin - Narrower
Concept UI M0350806
Preferred term Rondomycin
Physiomycine - Narrower
Concept UI M0013540
Preferred term Physiomycine
Lysocline - Narrower
Concept UI M0474829
Preferred term Lysocline
Methacycline Monohydrochloride - Narrower
Concept UI M0330127
Preferred term Methacycline Monohydrochloride
Entry term(s) Monohydrochloride, Methacycline



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