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Descriptor English: Clobazam
Descriptor Spanish: Clobazam
Descriptor clobazam
Entry term(s) 1-fenil-5-metil-8-cloro-1,2,4,5-tetrahidro-2,4-diceto-3H-1,5-benzodiazepina
Frisium
HR 376
LM 2717
LM-2717
LM2717
Onfi
Urbanyl
Scope note: Derivado benzodiacepínico que es un agonista de los RECEPTORES GABA-A de acción prolongada. Se usa como antiepiléptico en el tratamiento de las CONVULSIONES, incluidas las asociadas al SÍNDROME DE LENNOX-GASTAUT. También se usa como ansiolítico para el tratamiento a corto plazo de la ANSIEDAD aguda.
Descriptor Portuguese: Clobazam
Descriptor French: Clobazam
Entry term(s): Frisium
HR 376
LM-2717
Onfi
Urbanyl
Tree number(s): D03.633.100.079.080.165
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078306
Scope note: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anticonvulsants
Anti-Anxiety Agents
GABA-A Receptor Agonists
Registry Number: 2MRO291B4U
CAS Type 1 Name: 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 7-chloro-1-methyl-5-phenyl-
DeCS ID: 57798
Unique ID: D000078306
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2019/04/29
Clobazam - Preferred
Concept UI M0059171
Preferred term Clobazam
Urbanyl - Narrower
Concept UI M0059170
Preferred term Urbanyl
Onfi - Narrower
Concept UI M0589401
Preferred term Onfi
HR 376 - Narrower
Concept UI M0059169
Preferred term HR 376
LM-2717 - Narrower
Concept UI M0589402
Preferred term LM-2717
Frisium - Narrower
Concept UI M0059168
Preferred term Frisium



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