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Descriptor English: Olanzapine
Descriptor Spanish: Olanzapina
Descriptor olanzapina
Entry term(s) 2-metil-4-(4-metil-1-piperazinil)-10H-tieno(2,3-b)(1,5)benzodiacepina
LY 170052
LY 170053
LY-170052
LY170052
Zolafren
Zyprexa
pamoato de olanzapina
Scope note: Derivado benzodiacepínico que se une a los RECEPTORES DE SEROTONINA, RECEPTORES MUSCARÍNICOS, RECEPTORES HISTAMÍNICOS H1, RECEPTORES ADRENÉRGICOS ALFA-1 y RECEPTORES DE DOPAMINA. Es un antipsicótico que se usa en el tratamiento de la ESQUIZOFRENIA, el TRASTORNO BIPOLAR y el TRASTORNO DEPRESIVO MAYOR; también puede reducir las náuseas y los vómitos en pacientes que reciben quimioterapia.
Descriptor Portuguese: Olanzapina
Descriptor French: Olanzapine
Entry term(s): 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
LY 170052
LY 170053
LY-170052
LY170052
Olanzapine Pamoate
Zolafren
Zyprexa
Tree number(s): D03.633.100.079.080.738
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077152
Scope note: A benzodiazepine derivative that binds SEROTONIN RECEPTORS; MUSCARINIC RECEPTORS; HISTAMINE H1 RECEPTORS; ADRENERGIC ALPHA-1 RECEPTORS; and DOPAMINE RECEPTORS. It is an antipsychotic agent used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER; and MAJOR DEPRESSIVE DISORDER; it may also reduce nausea and vomiting in patients undergoing chemotherapy.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiemetics
Antipsychotic Agents
Serotonin Uptake Inhibitors
Registry Number: N7U69T4SZR
Public MeSH Note: 2019; OLANZAPINE was indexed under BENZODIAZEPINES 1992-2018
History Note: 2019 (1992)
DeCS ID: 57522
Unique ID: D000077152
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2019/05/28
Olanzapine - Preferred
Concept UI M0204623
Scope note A benzodiazepine derivative that binds SEROTONIN RECEPTORS; MUSCARINIC RECEPTORS; HISTAMINE H1 RECEPTORS; ADRENERGIC ALPHA-1 RECEPTORS; and DOPAMINE RECEPTORS. It is an antipsychotic agent used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER; and MAJOR DEPRESSIVE DISORDER; it may also reduce nausea and vomiting in patients undergoing chemotherapy.
Preferred term Olanzapine
Entry term(s) 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
LY-170052 - Narrower
Concept UI M0204621
Preferred term LY-170052
Entry term(s) LY 170052
LY170052
Zyprexa - Narrower
Concept UI M0204622
Preferred term Zyprexa
Zolafren - Narrower
Concept UI M000639460
Preferred term Zolafren
LY 170053 - Narrower
Concept UI M0204620
Preferred term LY 170053
Olanzapine Pamoate - Narrower
Concept UI M0535637
Preferred term Olanzapine Pamoate



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