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Descriptor English: Clobazam
Descriptor Spanish: Clobazam
Descriptor Portuguese: Clobazam
Descriptor French: Clobazam
Entry term(s): 1-Phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3H-1,5-benzodiazepine
Frisium
HR 376
LM 2717
LM-2717
LM2717
Onfi
Urbanyl
Tree number(s): D03.633.100.079.080.165
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078306
Scope note: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Anti-Anxiety Agents
GABA-A Receptor Agonists
Registry Number: 2MRO291B4U
CAS Type 1 Name: 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 7-chloro-1-methyl-5-phenyl-
Public MeSH Note: 2019; CLOBAZAM was indexed under BENZODIAZEPINES 1976-2018
History Note: 2019 (1976)
DeCS ID: 57798
Unique ID: D000078306
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2019/04/29
Clobazam - Preferred
Concept UI M0059171
Scope note A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
Preferred term Clobazam
Urbanyl - Narrower
Concept UI M0059170
Preferred term Urbanyl
Onfi - Narrower
Concept UI M0589401
Preferred term Onfi
1-Phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3H-1,5-benzodiazepine - Related but not broader or narrower
Concept UI M000642449
Preferred term 1-Phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3H-1,5-benzodiazepine
HR 376 - Narrower
Concept UI M0059169
Preferred term HR 376
LM-2717 - Narrower
Concept UI M0589402
Preferred term LM-2717
Entry term(s) LM 2717
LM2717
Frisium - Narrower
Concept UI M0059168
Preferred term Frisium



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