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Descriptor English: Oxcarbazepine
Descriptor Spanish: Oxcarbazepina
Descriptor oxcarbazepina
Entry term(s) 10,11-dihidro-10-oxo-5H-dibenz(b,f)azepina-5-carboxamida
GP 47680
timox
trileptal
Scope note: Derivado carbamacepínico que actúa como bloqueador de los canales del sodio dependientes de voltaje. Se usa para el tratamiento de las EPILEPSIAS PARCIALES con o sin generalización secundaria. También es un inductor del CITOCROMO P-450, miembro CYP3A4.
Descriptor Portuguese: Oxcarbazepina
Descriptor French: Oxcarbazépine
Entry term(s): 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
GP 47680
Timox
Trileptal
Tree number(s): D03.633.300.240.127.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078330
Scope note: A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Voltage-Gated Sodium Channel Blockers
Cytochrome P-450 CYP3A Inducers
Registry Number: VZI5B1W380
CAS Type 1 Name: 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10-oxo-
Public MeSH Note: 2019; OXCARBAZEPINE was indexed under CARBAMAZEPINE/analogs & derivatives 1982-2018
History Note: 2019 (1982)
DeCS ID: 57806
Unique ID: D000078330
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Oxcarbazepine - Preferred
Concept UI M0109945
Scope note A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.
Preferred term Oxcarbazepine
Entry term(s) 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
Trileptal - Narrower
Concept UI M0397883
Preferred term Trileptal
Timox - Narrower
Concept UI M0466842
Preferred term Timox
GP 47680 - Narrower
Concept UI M0109944
Preferred term GP 47680



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