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Descriptor English: Mirtazapine
Descriptor Spanish: Mirtazapina
Descriptor mirtazapina
Entry term(s) (N-metil-11C)mirtazapina
(S)-mirtazapina
6 azamianserina
6-azamianserina
ORG 3770
ORG-3770
ORG3770
Org 50081
esmirtazapina
norset
remergil
remeron
rexer
zispin
Scope note: Compuesto tetracíclico piperacinoacepínico que potencia la liberación de NORADRENALINA y SEROTONINA mediante el bloqueo de los RECEPTORES ADRENÉRGICOS ALFA-2 presinápticos. También bloquea los receptores de serotonina 5-HT2 y 5-HT3 y es un potente antagonista de los RECEPTORES HISTAMÍNICOS H1. Se usa para el tratamiento de la depresión, y también puede ser útil para el tratamiento de los trastornos de ansiedad.
Descriptor Portuguese: Mirtazapina
Descriptor French: Mirtazapine
Entry term(s): (N-Methyl-11C)mirtazapine
(S)-Mirtazapine
6 Azamianserin
6-Azamianserin
Esmirtazapine
Norset
ORG 3770
ORG-3770
ORG3770
Org 50081
Remergil
Remeron
Rexer
Zispin
Tree number(s): D03.633.300.240.588
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078785
Scope note: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents
Histamine H1 Antagonists
Anti-Anxiety Agents
Adrenergic alpha-2 Receptor Antagonists
Serotonin 5-HT2 Receptor Antagonists
Serotonin 5-HT3 Receptor Antagonists
Registry Number: A051Q2099Q
Public MeSH Note: 2019; MIRTAZAPINE was indexed under MIANSERIN/analogs & derivatives 1982-2018
History Note: 2019 (1982)
DeCS ID: 57855
Unique ID: D000078785
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/02
Mirtazapine - Preferred
Concept UI M0107850
Scope note A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Preferred term Mirtazapine
Entry term(s) 6 Azamianserin
6-Azamianserin
ORG 3770 - Narrower
Concept UI M0107846
Preferred term ORG 3770
Entry term(s) ORG-3770
ORG3770
Rexer - Narrower
Concept UI M0474342
Preferred term Rexer
Remeron - Narrower
Concept UI M0107848
Preferred term Remeron
Entry term(s) Norset
Remergil
Zispin
Esmirtazapine - Narrower
Concept UI M000615897
Preferred term Esmirtazapine
Entry term(s) (S)-Mirtazapine
Org 50081 - Narrower
Concept UI M000615898
Preferred term Org 50081
(N-Methyl-11C)mirtazapine - Narrower
Concept UI M0455874
Preferred term (N-Methyl-11C)mirtazapine



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