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Descriptor English: Mianserin
Descriptor Spanish: Mianserina
Descriptor mianserina
Scope note: Compuesto tetracíclico con efectos antidepresivos. Puede causar somnolencia y problemas hematológicos. Su mecanismo de acción terapéutica aún no se conoce bien, aunque aparentemente bloquea los receptores alfa-adrenérgicos, receptor H1 de histamina y algunos tipos de receptores de serotonina.
Descriptor Portuguese: Mianserina
Descriptor French: Miansérine
Entry term(s): Hydrochloride, Mianserin
Lerivon
Mianserin Hydrochloride
Mianserin Monohydrochloride
Monohydrochloride, Mianserin
Org GB 94
Tolvon
Tree number(s): D03.633.300.240.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008803
Scope note: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adrenergic alpha-Antagonists
Histamine H1 Antagonists
Serotonin Antagonists
Antidepressive Agents, Second-Generation
Registry Number: 250PJI13LM
CAS Type 1 Name: Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Previous Indexing: Dibenzazepines (1972-1974)
Pyrazines (1972-1974)
Public MeSH Note: 87; was see under DIBENZAZEPINES 1975-86
History Note: 87(75); was see under DIBENZAZEPINES 1975-86
DeCS ID: 8993
Unique ID: D008803
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Mianserin - Preferred
Concept UI M0013724
Scope note A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
Preferred term Mianserin
Mianserin Hydrochloride - Narrower
Concept UI M0330033
Preferred term Mianserin Hydrochloride
Entry term(s) Hydrochloride, Mianserin
Mianserin Monohydrochloride
Monohydrochloride, Mianserin
Tolvon - Narrower
Concept UI M0354041
Preferred term Tolvon
Lerivon - Narrower
Concept UI M0354021
Preferred term Lerivon
Org GB 94 - Narrower
Concept UI M0013725
Preferred term Org GB 94



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