Descriptor English: | Mirtazapine | ||||||
Descriptor Spanish: |
Mirtazapina
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Descriptor Portuguese: | Mirtazapina | ||||||
Descriptor French: | Mirtazapine | ||||||
Entry term(s): |
(N-Methyl-11C)mirtazapine (S)-Mirtazapine 6 Azamianserin 6-Azamianserin Esmirtazapine Norset ORG 3770 ORG-3770 ORG3770 Org 50081 Remergil Remeron Rexer Zispin |
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Tree number(s): |
D03.633.300.240.588 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000078785 | ||||||
Scope note: | A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Antidepressive Agents Antidepresivos Antidepressivos Antidépresseurs antidepresivos Histamine H1 Antagonists Antagonistas de los Receptores Histamínicos H1 Antagonistas dos Receptores Histamínicos H1 Antihistaminiques des récepteurs H1 antagonistas de los receptores histamínicos H1 Anti-Anxiety Agents Ansiolíticos Ansiolíticos Anxiolytiques ansiolíticos Adrenergic alpha-2 Receptor Antagonists Antagonistas de Receptores Adrenérgicos alfa 2 Antagonistas de Receptores Adrenérgicos alfa 2 Antagonistes des récepteurs alpha-2 adrénergiques antagonistas de receptores adrenérgicos alfa-2 Serotonin 5-HT2 Receptor Antagonists Antagonistas del Receptor de Serotonina 5-HT2 Antagonistas do Receptor 5-HT2 de Serotonina Antagonistes des récepteurs 5-HT2 de la sérotonine antagonistas de receptores de serotonina 5-HT2 Serotonin 5-HT3 Receptor Antagonists Antagonistas del Receptor de Serotonina 5-HT3 Antagonistas do Receptor 5-HT3 de Serotonina Antagonistes des récepteurs 5-HT3 de la sérotonine antagonistas de receptores de serotonina 5-HT3 |
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Registry Number: | A051Q2099Q | ||||||
Public MeSH Note: | 2019; MIRTAZAPINE was indexed under MIANSERIN/analogs & derivatives 1982-2018 |
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History Note: | 2019 (1982) |
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DeCS ID: | 57855 | ||||||
Unique ID: | D000078785 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2019/01/01 | ||||||
Date of Entry: | 2018/07/09 | ||||||
Revision Date: | 2018/07/02 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
Mirtazapine
- Preferred
ORG 3770
- Narrower
Rexer
- Narrower
Remeron
- Narrower
Esmirtazapine
- Narrower
Org 50081
- Narrower
(N-Methyl-11C)mirtazapine
- Narrower
Concept UI |
M0107850 |
Scope note | A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders. |
Preferred term | Mirtazapine |
Entry term(s) |
6 Azamianserin 6-Azamianserin |
Concept UI |
M0107846 |
Preferred term | ORG 3770 |
Entry term(s) |
ORG-3770 ORG3770 |
Concept UI |
M0474342 |
Preferred term | Rexer |
Concept UI |
M0107848 |
Preferred term | Remeron |
Entry term(s) |
Norset Remergil Zispin |
Concept UI |
M000615897 |
Preferred term | Esmirtazapine |
Entry term(s) |
(S)-Mirtazapine |
Concept UI |
M000615898 |
Preferred term | Org 50081 |
Concept UI |
M0455874 |
Preferred term | (N-Methyl-11C)mirtazapine |
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