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Descriptor English: Mirtazapine
Descriptor Spanish: Mirtazapina
Descriptor mirtazapina
Entry term(s) (N-metil-11C)mirtazapina
(S)-mirtazapina
6 azamianserina
6-azamianserina
ORG 3770
ORG-3770
ORG3770
Org 50081
esmirtazapina
norset
remergil
remeron
rexer
zispin
Scope note: Compuesto tetracíclico piperacinoacepínico que potencia la liberación de NORADRENALINA y SEROTONINA mediante el bloqueo de los RECEPTORES ADRENÉRGICOS ALFA-2 presinápticos. También bloquea los receptores de serotonina 5-HT2 y 5-HT3 y es un potente antagonista de los RECEPTORES HISTAMÍNICOS H1. Se usa para el tratamiento de la depresión, y también puede ser útil para el tratamiento de los trastornos de ansiedad.
Descriptor Portuguese: Mirtazapina
Descriptor French: Mirtazapine
Entry term(s): (N-Methyl-11C)mirtazapine
(S)-Mirtazapine
6 Azamianserin
6-Azamianserin
Esmirtazapine
Norset
ORG 3770
ORG-3770
ORG3770
Org 50081
Remergil
Remeron
Rexer
Zispin
Tree number(s): D03.633.300.240.588
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078785
Scope note: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents
Antidepresivos
Antidepressivos
Antidépresseurs
antidepresivos
Histamine H1 Antagonists
Antagonistas de los Receptores Histamínicos H1
Antagonistas dos Receptores Histamínicos H1
Antihistaminiques des récepteurs H1
antagonistas de los receptores histamínicos H1
Anti-Anxiety Agents
Ansiolíticos
Ansiolíticos
Anxiolytiques
ansiolíticos
Adrenergic alpha-2 Receptor Antagonists
Antagonistas de Receptores Adrenérgicos alfa 2
Antagonistas de Receptores Adrenérgicos alfa 2
Antagonistes des récepteurs alpha-2 adrénergiques
antagonistas de receptores adrenérgicos alfa-2
Serotonin 5-HT2 Receptor Antagonists
Antagonistas del Receptor de Serotonina 5-HT2
Antagonistas do Receptor 5-HT2 de Serotonina
Antagonistes des récepteurs 5-HT2 de la sérotonine
antagonistas de receptores de serotonina 5-HT2
Serotonin 5-HT3 Receptor Antagonists
Antagonistas del Receptor de Serotonina 5-HT3
Antagonistas do Receptor 5-HT3 de Serotonina
Antagonistes des récepteurs 5-HT3 de la sérotonine
antagonistas de receptores de serotonina 5-HT3
Registry Number: A051Q2099Q
Public MeSH Note: 2019; MIRTAZAPINE was indexed under MIANSERIN/analogs & derivatives 1982-2018
History Note: 2019 (1982)
DeCS ID: 57855
Unique ID: D000078785
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/02
Mirtazapine - Preferred
Concept UI M0107850
Scope note A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Preferred term Mirtazapine
Entry term(s) 6 Azamianserin
6-Azamianserin
ORG 3770 - Narrower
Concept UI M0107846
Preferred term ORG 3770
Entry term(s) ORG-3770
ORG3770
Rexer - Narrower
Concept UI M0474342
Preferred term Rexer
Remeron - Narrower
Concept UI M0107848
Preferred term Remeron
Entry term(s) Norset
Remergil
Zispin
Esmirtazapine - Narrower
Concept UI M000615897
Preferred term Esmirtazapine
Entry term(s) (S)-Mirtazapine
Org 50081 - Narrower
Concept UI M000615898
Preferred term Org 50081
(N-Methyl-11C)mirtazapine - Narrower
Concept UI M0455874
Preferred term (N-Methyl-11C)mirtazapine



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