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Descriptor English: gamma-Glutamylcyclotransferase
Descriptor Spanish: gamma-Glutamilciclotransferasa
Descriptor gamma-glutamilciclotransferasa
Entry term(s) gammaglutamilciclotransferasa
Scope note: Enzima que cataliza la síntesis de piroglutamato a partir de un gamma-glutamil-aminoácido, liberando también el aminoácido libre. La enzima actúa en derivados de glutamato, 2-aminobutirato, alanina y glicina. Se ha propuesto que la enzima pudiera intervenir en un ciclo del gamma-glutamilo para el transporte de aminoácidos al interior de las células en el intestino. EC 2.3.2.4.
Descriptor Portuguese: gama-Glutamilciclotransferase
Descriptor French: Gamma-glutamylcyclotransferase
Entry term(s): Cyclotransferase, gamma-Glutamylamine
gamma Glutamylamine Cyclotransferase
gamma Glutamylcyclotransferase
gamma-Glutamylamine Cyclotransferase
Tree number(s): D08.811.913.050.200.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005722
Scope note: An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines. EC 2.3.2.4.
Annotation: do not confuse with GAMMA-GLUTAMYLTRANSFERASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.2.4
CAS Type 1 Name: (5-L-Glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
Previous Indexing: Acyltransferases (1970-1974)
Glutamates (1970-1974)
Pyrrolidonecarboxylic Acid (1972-1974)
Public MeSH Note: 91; was see under ACYLTRANSFERASES 1975-90
History Note: 91(75); was see under ACYLTRANSFERASES 1975-90
DeCS ID: 5861
Unique ID: D005722
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09
gamma-Glutamylcyclotransferase - Preferred
Concept UI M0008976
Scope note An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines. EC 2.3.2.4.
Preferred term gamma-Glutamylcyclotransferase
Entry term(s) Cyclotransferase, gamma-Glutamylamine
gamma Glutamylamine Cyclotransferase
gamma Glutamylcyclotransferase
gamma-Glutamylamine Cyclotransferase



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