Search
Descriptor English: Hot Melt Extrusion Technology
Descriptor Spanish: Tecnología de Extrusión de Fusión en Caliente
Descriptor tecnología de extrusión por fusión en caliente
Entry term(s) extrusión por fusión en caliente
Scope note: Método sin disolventes para preparar numerosos tipos de sistemas de administración de fármacos y formas farmacéuticas para principios activos farmacéuticos que tienen problemas de solubilidad. Consiste en el bombeo de materiales poliméricos a temperaturas superiores a su temperatura de transición vítrea para mezclarlos en principios activos farmacéuticos con o sin aglutinantes, formándose así un producto amorfo con un aumento del perfil de disolución para los principios activos farmacéuticos.
Descriptor Portuguese: Tecnologia de Extrusão por Fusão a Quente
Descriptor French: Technologie d'extrusion par fusion à chaud
Entry term(s): Hot Melt Extrusion
Tree number(s): E05.916.840
J01.897.360.500
J01.897.836.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000080048
Scope note: Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients.
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 2020
History Note: 2020
DeCS ID: 59125
Unique ID: D000080048
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/05/30
Hot Melt Extrusion Technology - Preferred
Concept UI M000646243
Scope note Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients.
Preferred term Hot Melt Extrusion Technology
Entry term(s) Hot Melt Extrusion



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey