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Descriptor English: T Follicular Helper Cells
Descriptor Spanish: Células T Auxiliares Foliculares
Descriptor linfocitos T colaboradores foliculares
Entry term(s) linfocitos T colaboradores de los folículos de linfocitos B
linfocitos Tfh
Scope note: Subpoblación especializada de linfocitos T CD4+ implicados en la formación del CENTRO GERMINAL. Los linfocitos Tfh se encuentran principalmente en órganos linfáticos secundarios, tales como la TONSILA PALATINA, el BAZO y los GANGLIOS LINFÁTICOS. Son positivos para los ANTÍGENOS CD4, los ANTÍGENOS CD45, la PROTEÍNA C-BCL-6, los RECEPTORES CXCR5, la PROTEÍNA COESTIMULADORA DE LINFOCITOS T INDUCIBLES (ICOS) y el RECEPTOR PD-1.
Descriptor Portuguese: Células T Auxiliares Foliculares
Descriptor French: Lymphocytes T auxiliaires folliculaires
Entry term(s): Follicular B Helper T Cells
Follicular Helper T Cells
Tfh Cell
Tfh Cells
Tree number(s): A11.118.637.555.567.550.500.400.450
A11.118.637.555.567.569.200.400.450
A11.118.637.555.567.569.500.400.450
A15.145.229.637.555.567.550.500.400.250
A15.145.229.637.555.567.569.200.400.250
A15.382.490.555.567.550.500.400.450
A15.382.490.555.567.569.200.400.450
A15.382.490.555.567.569.500.400.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000084522
Scope note: A specialized subpopulation of CD4+ T cells involved in formation of GERMINAL CENTER. Tfh cells are mostly located in secondary lymphoid organs, e.g., TONSIL; SPLEEN and LYMPH NODES. They are CD4 ANTIGEN; CD45 ANTIGEN; B-CELL LYMPHOMA 6 PROTEIN; CXCR5 RECEPTORS; ICOS INDUCIBLE T-CELL CO-STIMULATOR; and PD1 RECEPTOR positive.
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: T-Lymphocytes, Helper-Inducer(2004-2020)
Public MeSH Note: 2021
History Note: 2021
DeCS ID: 59427
Unique ID: D000084522
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2021/01/01
Date of Entry: 2020/07/07
Revision Date: 2020/05/27
T Follicular Helper Cells - Preferred
Concept UI M000682877
Scope note A specialized subpopulation of CD4+ T cells involved in formation of GERMINAL CENTER. Tfh cells are mostly located in secondary lymphoid organs, e.g., TONSIL; SPLEEN and LYMPH NODES. They are CD4 ANTIGEN; CD45 ANTIGEN; B-CELL LYMPHOMA 6 PROTEIN; CXCR5 RECEPTORS; ICOS INDUCIBLE T-CELL CO-STIMULATOR; and PD1 RECEPTOR positive.
Preferred term T Follicular Helper Cells
Entry term(s) Follicular B Helper T Cells
Follicular Helper T Cells
Tfh Cell
Tfh Cells



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