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Descriptor English: Lamellar Bodies
Descriptor Spanish: Cuerpos Lamelares
Descriptor cuerpos laminares
Entry term(s) cuerpos de Odland
gránulos de recubrimiento de la membrana
gránulos laminares
lisosomas laminares
Scope note: Orgánulos endolisosómicos rodeados de LÍPIDOS DE MEMBRANAS multilaminares. Intervienen en diversas funciones en el almacenamiento y la secreción de LÍPIDOS celulares. Los cuerpos laminares en los NEUMOCITOS de tipo 2 producen y secretan SURFACTANTES PULMONARES (por ejemplo, dipalmitoil fosfatidilcolina). Los cuerpos laminares en la piel producen y secretan lípidos neutros para proporcionar una barrera hidrófoba. Se sabe que ocurre una acumulación patológica de cuerpos laminares en enfermedades por almacenamiento de lípidos (por ejemplo, DEFICIENCIA DE LA LECITINA ACILTRANSFERASA y SÍNDROME DE HERMANSKY-PUDLAK).
Descriptor Portuguese: Corpos Lamelares
Descriptor French: Corps lamellaires
Entry term(s): Body, Lamellar
Granule, Lamellar
Granule, Membrane Coating
Granule, Membrane-Coating
Lamellar Body
Lamellar Granule
Lamellar Granules
Lamellar Lysosome
Lamellar Lysosomes
Lysosome, Lamellar
Membrane Coating Granule
Membrane Coating Granules
Membrane-Coating Granule
Membrane-Coating Granules
Odland Bodies
Tree number(s): A11.284.430.214.190.500.384
A11.284.430.214.190.875.190.190.472
A11.284.430.214.190.875.190.880.810.375
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000088502
Scope note: Endolysosomal organelles surrounded by multi-lamellar MEMBRANE LIPIDS. They are involved in diverse functions in storage and secretion of cellular LIPIDS. Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g., DIPALMITOYL PHOSPHATIDYLCHOLINE). Lamellar bodies in the skin produce and secrete neutral lipids to provide hydrophobic barrier. Pathological accumulation of lamellar bodies are also known in lipid storage diseases (e.g.,LCAT DEFICIENCY; and HERMANSKY-PUDLAK SYNDROME).
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Public MeSH Note: 2022
History Note: 2022
DeCS ID: 59684
Unique ID: D000088502
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/01
Lamellar Bodies - Preferred
Concept UI M000741412
Scope note Endolysosomal organelles surrounded by multi-lamellar MEMBRANE LIPIDS. They are involved in diverse functions in storage and secretion of cellular LIPIDS. Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g., DIPALMITOYL PHOSPHATIDYLCHOLINE). Lamellar bodies in the skin produce and secrete neutral lipids to provide hydrophobic barrier. Pathological accumulation of lamellar bodies are also known in lipid storage diseases (e.g.,LCAT DEFICIENCY; and HERMANSKY-PUDLAK SYNDROME).
Preferred term Lamellar Bodies
Entry term(s) Body, Lamellar
Granule, Lamellar
Granule, Membrane Coating
Granule, Membrane-Coating
Lamellar Body
Lamellar Granule
Lamellar Granules
Lamellar Lysosome
Lamellar Lysosomes
Lysosome, Lamellar
Membrane Coating Granule
Membrane Coating Granules
Membrane-Coating Granule
Membrane-Coating Granules
Odland Bodies



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