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Descriptor English: Iodothyronine Deiodinase Type II
Descriptor Spanish: Yodotironina Deyodinasa Tipo II
Descriptor yodotironina-desyodasa de tipo II
Entry term(s) 5'-desyodasa de tipo II
desyodasa de tipo 2 (D2)
enzima DIO2
enzima TXDI2
selenodesyodasa de tipo 2
Scope note: Enzima responsable de la conversión de T4 (3,5,3',5'-tetrayodotironina) en T3 (3,5,3'-TRIYODOTIRONINA). Puede contribuir a aumentar la producción de HORMONA TIROIDEA T3 en pacientes con ENFERMEDAD DE GRAVES.
Descriptor Portuguese: Iodotironina Desiodinase Tipo II
Descriptor French: Without translation
Entry term(s): 2 Selenodeiodinase, Type
2, Selenodeiodinase Type
5'-Deiodinase, Type II
DIO2 Enzyme
Enzyme, DIO2
Enzyme, TXDI2
II 5'-Deiodinase, Type
Selenodeiodinase Type 2
Selenodeiodinase, Type 2
TXDI2 Enzyme
Type 2 Deiodinase (D2)
Type 2 Selenodeiodinase
Type 2, Selenodeiodinase
Type II 5' Deiodinase
Type II 5'-Deiodinase
Type II Iodothyronine Deiodinase
Tree number(s): D08.811.682.732.525.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097564
Scope note: An enzyme responsible for T4 (3,5,3',5'-tetraiodothyronine) to T3 (3,5,3'-TRIIODOTHYRONINE) conversion. May contribute to increasing T3 THYROID HORMONE production in patients with GRAVES DISEASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.11.1.-
Public MeSH Note: 2024; IODOTHYRONINE DEIODINASE TYPE II was indexed under IODIDE PEROXIDASE 1996-2023
History Note: 2024 (1996)
DeCS ID: 60593
Unique ID: D000097564
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/30
Iodothyronine Deiodinase Type II - Preferred
Concept UI M0267541
Scope note An enzyme responsible for T4 (3,5,3',5'-tetraiodothyronine) to T3 (3,5,3'-TRIIODOTHYRONINE) conversion. May contribute to increasing T3 THYROID HORMONE production in patients with GRAVES DISEASE.
Preferred term Iodothyronine Deiodinase Type II
Entry term(s) 2 Selenodeiodinase, Type
2, Selenodeiodinase Type
5'-Deiodinase, Type II
DIO2 Enzyme
Enzyme, DIO2
Enzyme, TXDI2
II 5'-Deiodinase, Type
Selenodeiodinase Type 2
Selenodeiodinase, Type 2
TXDI2 Enzyme
Type 2 Deiodinase (D2)
Type 2 Selenodeiodinase
Type 2, Selenodeiodinase
Type II 5' Deiodinase
Type II 5'-Deiodinase
Type II Iodothyronine Deiodinase



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