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Descriptor English: Aminoglutethimide
Descriptor Spanish: Aminoglutetimida
Descriptor aminoglutetimida
Scope note: Inhibidor de la aromatasa que produce un estado de adrenalectomía "clínica" bloqueando la producción de esteroides adrenales. Asimismo, bloquea la conversión de andrógenos a estrógenos. La aminoglutetimida se ha utilizado en el tratamiento de los cánceres avanzados de mama y próstata. Antiguamente se utilizó como anticonvulsivante suave. (Martindale, The Extra Pharmacopoeia, 30th ed, p454)
Descriptor Portuguese: Aminoglutetimida
Descriptor French: Aminoglutéthimide
Entry term(s): Cytadren
Orimeten
Tree number(s): D03.383.621.808.425.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000616
Scope note: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents, Hormonal
Aromatase Inhibitors
Registry Number: 0O54ZQ14I9
CAS Type 1 Name: 2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-
DeCS ID: 625
Unique ID: D000616
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Aminoglutéthimide - Preferred
Concept UI M0000944
Preferred term Aminoglutéthimide
Cytadren - Narrower
Concept UI M0000945
Preferred term Cytadren
Entry term(s) Orimeten



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