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Descriptor English: Amiodarone
Descriptor Spanish: Amiodarona
Descriptor amiodarona
Scope note: Fármaco antianginoso y antiarrítmico de clase III. Incrementa la duración de la acción del músculo ventricular y atrial, por inhibición de los CANALES DE POTASIO y de los CANALES DE SODIO ACTIVADOS POR VOLTAJE. Como consecuencia se produce disminución de la frecuencia cardíaca y de la resistencia vascular.
Descriptor Portuguese: Amiodarona
Descriptor French: Amiodarone
Entry term(s): Amiobeta
Amiodarex
Amiodarona
Amiodarone Hydrochloride
Amiohexal
Aratac
Braxan
Corbionax
Cordarex
Cordarone
Hydrochloride, Amiodarone
Kordaron
L 3428
L-3428
L3428
Ortacrone
Rytmarone
SKF 33134 A
SKF 33134-A
SKF 33134A
Tachydaron
Trangorex
Tree number(s): D03.633.100.127.075
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000638
Scope note: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Arrhythmia Agents
Vasodilator Agents
Potassium Channel Blockers
Sodium Channel Blockers
Cytochrome P-450 CYP1A2 Inhibitors
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2D6 Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: N3RQ532IUT
CAS Type 1 Name: Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-
Previous Indexing: Benzofurans (1968-1974)
Diethylamines (1974)
Iodobenzoates (1973-1974)
Public MeSH Note: 87; was see under BENZOFURANS 1975-86
History Note: 87(75); was see under BENZOFURANS 1975-86
DeCS ID: 651
Unique ID: D000638
NLM Classification: QV 150
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1974/11/19
Revision Date: 2017/05/24
Amiodarone - Preferred
Concept UI M0000973
Scope note An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
Preferred term Amiodarone
Amiodarona - Narrower
Concept UI M0433211
Preferred term Amiodarona
Amiodarone Hydrochloride - Narrower
Concept UI M0582739
Preferred term Amiodarone Hydrochloride
Entry term(s) Hydrochloride, Amiodarone
Amiohexal - Narrower
Concept UI M0433212
Preferred term Amiohexal
Aratac - Narrower
Concept UI M0433213
Preferred term Aratac
Tachydaron - Narrower
Concept UI M0433221
Preferred term Tachydaron
Corbionax - Narrower
Concept UI M0433215
Preferred term Corbionax
Cordarone - Narrower
Concept UI M0433210
Preferred term Cordarone
Entry term(s) Amiodarex
Cordarex
Kordaron
Trangorex
L-3428 - Narrower
Concept UI M0353573
Preferred term L-3428
Entry term(s) L 3428
L3428
Ortacrone - Narrower
Concept UI M0433216
Preferred term Ortacrone
Rytmarone - Narrower
Concept UI M0433220
Preferred term Rytmarone
SKF 33134-A - Narrower
Concept UI M0353572
Preferred term SKF 33134-A
Entry term(s) SKF 33134 A
SKF 33134A
Amiobeta - Narrower
Concept UI M0433209
Preferred term Amiobeta
Braxan - Narrower
Concept UI M0433214
Preferred term Braxan



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