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Descriptor English: Hybridomas
Descriptor Spanish: Hibridomas
Descriptor hibridomas
Scope note: Células creadas artificialmente mediante la fusión de linfocitos activados con células neoplásicas. Las células híbridas resultantes se clonan y producen anticuerpos puros o 'monoclonales', o productos de células T, idénticos a aquellos producidos por las células progenitoras inmunocompetentes. También crecen y se dividen continuamente como las células neoplásicas progenitoras.
Descriptor Portuguese: Hibridomas
Descriptor French: Hybridomes
Entry term(s): Hybridoma
Tree number(s): A11.251.353.485
A11.251.600.485
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006825
Scope note: Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
Annotation: note category: not a tumor
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cell Fusion (1975-1981)
Cell Line (1975-1981)
Clone Cells (1975-1981)
Hybrid Cells (1975-1981)
Public MeSH Note: 82
History Note: 82
Related: Antibodies, Monoclonal MeSH
DeCS ID: 6977
Unique ID: D006825
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1982/01/01
Date of Entry: 1981/05/20
Revision Date: 2010/06/25
Hybridomas - Preferred
Concept UI M0010670
Scope note Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
Preferred term Hybridomas
Entry term(s) Hybridoma



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