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Descriptor English: Hydroxychloroquine
Descriptor Spanish: Hidroxicloroquina
Descriptor hidroxicloroquina
Entry term(s) oxicloroquina
Scope note: Agente quimioterapéutico que actúa contra las formas eritrocíticas de los parásitos de la malaria. La hidroxicloroquina parece concentrarse en las vacuolas alimentarias de los protozoarios afectados. Inhibe la heme polimerasa del plasmodio. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
Descriptor Portuguese: Hidroxicloroquina
Descriptor French: Hydroxychloroquine
Entry term(s): Hydroxychlorochin
Hydroxychloroquine Sulfate
Hydroxychloroquine Sulfate (1:1) Salt
Oxychlorochin
Oxychloroquine
Plaquenil
Tree number(s): D03.633.100.810.050.180.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006886
Scope note: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimalarials
Enzyme Inhibitors
Antirheumatic Agents
Registry Number: 4QWG6N8QKH
CAS Type 1 Name: ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-
DeCS ID: 7045
Unique ID: D006886
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Hydroxychloroquine - Preferred
Concept UI M0010751
Scope note A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
Preferred term Hydroxychloroquine
Entry term(s) Hydroxychlorochin
Oxychlorochin
Oxychloroquine
Plaquenil - Narrower
Concept UI M0010753
Preferred term Plaquenil
Hydroxychloroquine Sulfate - Narrower
Concept UI M0330264
Preferred term Hydroxychloroquine Sulfate
Entry term(s) Hydroxychloroquine Sulfate (1:1) Salt



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