| Descriptor English: | Hydroxymethylglutaryl CoA Reductases | ||||||
| Descriptor Spanish: |
Hidroximetilglutaril-CoA Reductasas
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| Descriptor Portuguese: | Hidroximetilglutaril-CoA Redutases | ||||||
| Descriptor French: | Hydroxymethylglutaryl-CoA reductases | ||||||
| Entry term(s): |
3 Hydroxy 3 methylglutaryl CoA Reductase 3-Hydroxy-3-methylglutaryl CoA Reductase CoA Reductase, 3-Hydroxy-3-methylglutaryl HMG CoA Reductase HMG CoA Reductases Hydroxymethylglutaryl CoA Reductase Reductase, 3-Hydroxy-3-methylglutaryl CoA |
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| Tree number(s): |
D08.811.682.047.820.150.415 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D006903 | ||||||
| Scope note: | Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Hydroxymethylglutaryl-CoA Reductase Inhibitors
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| Registry Number: | EC 1.1.1.- | ||||||
| Previous Indexing: |
Alcohol Oxidoreductases (1966-1977) Glutarates (1966-1974) Mevalonic Acid (1966-1974) |
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| Public MeSH Note: | 78; was see under ALCOHOL OXIDOREDUCTASES 1975-77 |
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| History Note: | 78(75); was see under ALCOHOL OXIDOREDUCTASES 1975-77 |
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| Related: |
Hydroxymethylglutaryl-CoA Reductase Inhibitors
MeSH | ||||||
| DeCS ID: | 7074 | ||||||
| Unique ID: | D006903 | ||||||
| NLM Classification: | QU 140 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1978/01/01 | ||||||
| Date of Entry: | 1974/11/11 | ||||||
| Revision Date: | 2013/07/08 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Hydroxymethylglutaryl CoA Reductases
- Preferred
| Concept UI |
M0010772 |
| Scope note | Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID. |
| Preferred term | Hydroxymethylglutaryl CoA Reductases |
| Entry term(s) |
3 Hydroxy 3 methylglutaryl CoA Reductase 3-Hydroxy-3-methylglutaryl CoA Reductase CoA Reductase, 3-Hydroxy-3-methylglutaryl HMG CoA Reductase HMG CoA Reductases Hydroxymethylglutaryl CoA Reductase Reductase, 3-Hydroxy-3-methylglutaryl CoA |
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