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Descriptor English: 2-Hydroxy-5-nitrobenzyl Bromide
Descriptor Spanish: 2-Hidroxi-5-nitrobencil Bromuro
Descriptor bromuro de 2-hidroxi-5-nitrobencilo
Entry term(s) reactivo I de Koshland
Scope note: Reactivo químico que reacciona con la porción de triptófano de las moléculas de proteínas y la modifica químicamente. Se utiliza para estudios enzimáticos de "sitio activo" y otros estudios de proteínas. En ocasiones recibe la denominación de reactivo de Koshland.
Descriptor Portuguese: 2-Hidroxi-5-nitrobenzil Brometo
Descriptor French: 2-Bromométhyl-4-nitro-phénol
Entry term(s): 2 Hydroxy 5 nitrobenzyl Bromide
Koshland Reagent
Koshland Reagent I
Koshland's Reagent I
Koshlands Reagent
Koshlands Reagent I
Reagent I, Koshland's
Reagent, Koshland
Reagent, Koshlands
Tree number(s): D02.455.426.559.389.140.400
D02.455.426.559.389.657.566.400
D02.640.743.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015077
Scope note: A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Indicators and Reagents
Registry Number: 772-33-8
CAS Type 1 Name: Phenol, 2-(bromomethyl)-4-nitro-
Previous Indexing: Benzyl Compounds (1973-1974)
Nitrophenols (1973-1974)
Public MeSH Note: 91; was see under NITROPHENOLS 1975-90
History Note: 91(75); was see under NITROPHENOLS 1975-90
DeCS ID: 7076
Unique ID: D015077
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2012/07/03
2-Hydroxy-5-nitrobenzyl Bromide - Preferred
Concept UI M0023190
Scope note A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Preferred term 2-Hydroxy-5-nitrobenzyl Bromide
Entry term(s) 2 Hydroxy 5 nitrobenzyl Bromide
Koshland Reagent
Koshland Reagent I
Koshland's Reagent I
Koshlands Reagent
Koshlands Reagent I
Reagent I, Koshland's
Reagent, Koshland
Reagent, Koshlands



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