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Descriptor English: Hyperparathyroidism, Secondary
Descriptor Spanish: Hiperparatiroidismo Secundario
Descriptor hiperparatiroidismo secundario
Scope note: Exceso de producción de la hormona paratiroidea (PTH) por las glándulas paratiroides (hiperplasia) secundaria a causas diversas (déficit de la vitamina D, malabsorción de la vitamina D, fármacos, etc.) y, sobre todo, por hipocalcemia crónica secundaria a insuficiencia renal crónica avanzada, que cursa con hiperfosforemia. La hipocalcemia es secundaria a la disminución de la síntesis renal de vitamina D activa (vitamina D3); ello induce una hipersecreción de PTH, que produce la movilización del calcio y del fósforo óseo. Dependiendo de la fase evolutiva, puede cursar con hipercalcemia, hiperfosforemia y osteodistrofia renal. Las manifestaciones clínicas son: dolores y deformidades óseas, miopatías, frecuente prurito, calcificación de las partes blandas, que pueden progresar a calcificaciones arteriales y viscerales, etc. Si no se trata, puede progresar a un hiperparatiroidismo terciario (autonomía funcional). Se previene mediante el control del metabolismo calcio-fósforo, a base de una dieta pobre en fósforo, quelantes del fósforo y vitamina D. (Diccionario Espasa de Medicina, ed. electrónica 2000)
Descriptor Portuguese: Hiperparatireoidismo Secundário
Descriptor French: Hyperparathyroïdie secondaire
Entry term(s): Hyperparathyroidisms, Secondary
Secondary Hyperparathyroidism
Secondary Hyperparathyroidisms
Tree number(s): C19.642.355.480
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006962
Scope note: Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Hyperparathyroidism (1966-1969)
Public MeSH Note: 70
History Note: 70
Entry Version: HYPERPARATHYROIDISM SECOND
DeCS ID: 7141
Unique ID: D006962
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1970/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Hyperparathyroidism, Secondary - Preferred
Concept UI M0010846
Scope note Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
Preferred term Hyperparathyroidism, Secondary
Entry term(s) Hyperparathyroidisms, Secondary
Secondary Hyperparathyroidism
Secondary Hyperparathyroidisms



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