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Descriptor English: Ligands
Descriptor Spanish: Ligandos
Descriptor ligandos
Entry term(s) ligando
Scope note: Moléculas que se unen a otra molécula. Se usa este término especialmente para referirse a una molécula pequeña que se une específicamente a una molécula grande, como la unión de un antígeno a un anticuerpo, la unión de una hormona o un neurotransmisor a un receptor, o la unión de un sustrato o un efector alostérico a una enzima. Un ligando es también una molécula que dona o acepta un par de electrones para formar un enlace covalente coordinado con el átomo metálico central de un complejo de coordinación. (Dorland, 27th ed)
Descriptor Portuguese: Ligantes
Descriptor French: Ligands
Entry term(s): Ligand
Tree number(s): D27.720.470.480
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008024
Scope note: A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
Annotation: IM general only; usually NIM with specific compound IM
Allowable Qualifiers: No qualifiers
Previous Indexing: Metals (1966-1972)
Organometallic Compounds (1968-1972)
Public MeSH Note: 74
History Note: 74(73)
Related: Radioligand Assay MeSH
Receptors, Cell Surface MeSH
DeCS ID: 8200
Unique ID: D008024
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Ligands - Preferred
Concept UI M0012508
Scope note A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
Preferred term Ligands
Entry term(s) Ligand



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