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Descriptor English: Mitomycins
Descriptor Spanish: Mitomicinas
Descriptor mitomicinas
Scope note: Grupo de metil azirino pirrol indol dionas obtenidas de ciertas cepas de Streptomyces. Son antibióticos muy tóxicos utilizados como AGENTES ANTINEOPLÁSICOS en algunos tumores sólidos. La PORFIROMICINA y la MITOMICINA son los miembros más útiles del grupo.
Descriptor Portuguese: Mitomicinas
Descriptor French: Mitomycines
Tree number(s): D02.806.400.249
D03.383.097.500
D03.633.100.473.412.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008937
Scope note: A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
Annotation: MITOMYCIN is also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Public MeSH Note: 82; was MITOMYCIN 1963-81
Online Note: use MITOMYCINS to search MITOMYCIN 1966-81
History Note: 82; was MITOMYCIN 1963-81
DeCS ID: 9127
Unique ID: D008937
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1982/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Mitomycins - Preferred
Concept UI M0013949
Scope note A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
Preferred term Mitomycins



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