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Descriptor English: Neuroblastoma
Descriptor Spanish: Neuroblastoma
Descriptor neuroblastoma
Scope note: Neoplasia que es frecuente en la primera infancia y surge de células de la cresta neural en el sistema nervioso simpático. Se caracteriza por un comportamiento clínico diverso, desde la remisión espontánea hasta una progresión metastásica rápida y la muerte. Este tumor es la neoplasia maligna intraabdominal más frecuente de la infancia, pero también puede surgir en tórax, cuelo, o raramente en el sistema nervioso central. Histológicamente se caracteriza por la presencia de células redondas unifromes con núcleos hipercromáticos dispuestos en nidos y separados por tabiques fibrovasculares. Los neuroblastomas pueden asociarse al síndrome del opsoclono-mioclono. (DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp. 2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Descriptor Portuguese: Neuroblastoma
Descriptor French: Neuroblastome
Entry term(s): Neuroblastomas
Tree number(s): C04.557.465.625.600.590.650.550
C04.557.470.670.590.650.550
C04.557.580.625.600.590.650.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009447
Scope note: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Annotation: coord IM with precoord organ/neopl term (IM); for NEUROBLASTOMA, RETINAL see RETINOBLASTOMA
Allowable Qualifiers: BL blood
BS blood supply
CF cerebrospinal fluid
CH chemistry
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SC secondary
SU surgery
TH therapy
UL ultrastructure
UR urine
VE veterinary
VI virology
DeCS ID: 9640
Unique ID: D009447
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Neuroblastoma - Preferred
Concept UI M0014699
Scope note A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Preferred term Neuroblastoma
Entry term(s) Neuroblastomas



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