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Descriptor English: Apamin
Descriptor Spanish: Apamina
Descriptor apamina
Scope note: Polipéptido muy neurotóxico que se obtiene del veneno de la abeja (Apis mellifera). Está formado por 18 aminoácidos con dos puentes disulfuro y causa hiperexcitabilidad, produciendo convulsiones y parálisis respiratoria.
Descriptor Portuguese: Apamina
Descriptor French: Apamine
Tree number(s): D20.888.065.115.060
D23.946.833.065.115.060
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001030
Scope note: A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.
Annotation: /antag permitted but consider also ANTIVENINS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 24345-16-2
CAS Type 1 Name: Apamin
Previous Indexing: Bees (1966-1977)
Venoms (1966-1977)
Public MeSH Note: 91; was see under BEE VENOMS 1978-90
History Note: 91(78); was see under BEE VENOMS 1978-90
DeCS ID: 1034
Unique ID: D001030
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/27
Revision Date: 2015/03/31
Apamin - Preferred
Concept UI M0001564
Scope note A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.
Preferred term Apamin



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