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Descriptor English: Melitten
Descriptor Spanish: Meliteno
Descriptor melitina
Entry term(s) mellitina
Scope note: Polipéptido básico del veneno de las abejas (Apis mellifera). Contiene 26 aminoácidos, tiene propiedades citolíticas, produce contractura muscular, libera histamina y rompe la tensión superficial, debido probablemente a la lisis de las membranas celulares y mitocondriales.
Descriptor Portuguese: Meliteno
Descriptor French: Mélittine
Entry term(s): Melittin
Mellitin
Tree number(s): D12.644.050.550
D12.644.066.500.550
D12.776.543.695.054.550
D20.888.065.115.580
D23.946.833.065.115.580
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008555
Scope note: Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.
Annotation: /antag permitted but consider also ANTIVENINS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 20449-79-0
CAS Type 1 Name: Melittin (honeybee)
Previous Indexing: Bees (1973-1974)
Peptides (1973-1974)
Venoms (1973-1974)
Public MeSH Note: 91; was see under BEE VENOMS 1978-90; was see under VENOMS 1975-77
History Note: 91(75); was see under BEE VENOMS 1978-90; was see under VENOMS 1975-77
DeCS ID: 8723
Unique ID: D008555
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2007/07/09
Melitten - Preferred
Concept UI M0013325
Scope note Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.
Preferred term Melitten
Entry term(s) Melittin
Mellitin



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