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Descriptor English: Apolipoproteins B
Descriptor Spanish: Apolipoproteínas B
Descriptor apolipoproteínas B
Entry term(s) Apo-B
Scope note: Proteínas estructurales mayores de las LIPOPROTEÍNAS ricas en triacilglicerol. Hay dos formas, la apolipoproteína B-100 y la apolipoproteína B-48, ambas derivadas de un único gen. La apoB-100 expresada en el hígado se encuentra en las lipoproteínas de baja densidad (LIPOPROTEÍNAS, LDL; LIPOPROTEÍNAS, VLDL). La apo-48 expresada en el intestino se encuentra en los QUILOMICRONES. Son importantes en la biosíntesis, transporte y metabolismo de las lipoproteínas ricas en triacilglicerol. Las concentraciones plasmáticas de apo-B son altas en los pacientes ateroscleróticos pero indetectables en la ABETALIPOPROTEINEMIA.
Descriptor Portuguese: Apolipoproteínas B
Descriptor French: Apolipoprotéines B
Entry term(s): Apo B
Apo-B
ApoB
Apoprotein (B)
Apoproteins B
Tree number(s): D10.532.091.300
D12.776.070.400.300
D12.776.521.120.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001055
Scope note: Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Apolipoproteins (1977-1984)
Public MeSH Note: 85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93
Online Note: use APOLIPOPROTEINS B to search APOLIPOPROTEIN B 1985-93
History Note: 85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93
Related: Abetalipoproteinemia MeSH
DeCS ID: 1061
Unique ID: D001055
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1984/05/25
Revision Date: 2006/07/05
Apolipoproteins B - Preferred
Concept UI M0001596
Scope note Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
Preferred term Apolipoproteins B
Entry term(s) Apo B
Apo-B
ApoB
Apoproteins B - Broader
Concept UI M0001598
Preferred term Apoproteins B
Entry term(s) Apoprotein (B)



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