| Descriptor English: | Arbaprostil | ||||||
| Descriptor Spanish: | 
                                Arbaprostilo                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Arbaprostilo | ||||||
| Descriptor French: | Arbaprostil | ||||||
| Entry term(s): | 
                                    15 Methylprostaglandin E2 15-Methylprostaglandin E2 Arbacet U 42842 U-42842 U42842  | 
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| Tree number(s): | 
                                        D10.251.355.255.550.775.450.050 D23.469.050.175.725.775.450.050 D23.469.700.660.050  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D001101 | ||||||
| Scope note: | A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Anti-Ulcer Agents | 
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| Registry Number: | M6B59S6MEF | ||||||
| CAS Type 1 Name: | Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (5Z,11alpha,13E,15R)- | ||||||
| Previous Indexing: | 
                                                Prostaglandins (1966-1974) Prostaglandins E (1975-1977) Prostaglandins E, Synthetic (1978-1979) Prostaglandins, Synthetic (1977)  | 
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| Public MeSH Note: | 91; was see under PROSTAGLANDINS E, SYNTHETIC 1980-90; 15-METHYLPROSTAGLANDIN E2 METHYL ESTER & METHYLDINOPROSTONE were see ARBAPROSTIL 1980-93 | 
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| Online Note: | use ARBAPROSTIL to search 15-METHYLPROSTAGLANDIN E2 METHYL ESTER & METHYLDINOPROSTONE 1980-93 | 
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| History Note: | 91(80); was see under PROSTAGLANDINS E, SYNTHETIC 1980-90; 15-METHYLPROSTAGLANDIN E2 METHYL ESTER & METHYLDINOPROSTONE were see ARBAPROSTIL 1980-93 | 
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| DeCS ID: | 1105 | ||||||
| Unique ID: | D001101 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1979/05/23 | ||||||
| Revision Date: | 2015/06/08 | 
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                                        CHEMICALS AND DRUGS
 
Lipids [D10]Lipids - 
                                    
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors - 
                                    
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors 
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                        Arbaprostil                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Arbacet                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        U-42842                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0001657 | 
                                
| Scope note | A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors. | 
| Preferred term | Arbaprostil | 
| Entry term(s) | 
                                        
                                                                                            15 Methylprostaglandin E2                                                 15-Methylprostaglandin E2  | 
                                
| Concept UI | 
                                        
                                        M0351563 | 
                                
| Preferred term | Arbacet | 
| Concept UI | 
                                        
                                        M0351562 | 
                                
| Preferred term | U-42842 | 
| Entry term(s) | 
                                        
                                                                                            U 42842                                                 U42842  | 
                                
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