Search
Descriptor English: 16,16-Dimethylprostaglandin E2
Descriptor Spanish: 16,16-Dimetilprostaglandina E2
Descriptor 16,16-dimetilprostaglandina E2
Scope note: Análogo sintético de la prostaglandina E que protege la mucosa gástrica, previene la ulceración y promueve la cicatrización de las úlceras pépticas. El efecto protector es independiente de la inhibición ácida. Es también un potente inhibidor de la función pancreática y del crecimiento de tumores experimentales.
Descriptor Portuguese: 16,16-Dimetilprostaglandina E2
Descriptor French: Diméthyl-16,16 prostaglandine E2
Entry term(s): 16,16 Dimethyl PGE2
16,16 Dimethylprostaglandin E2
16,16-Dimethyl-PGE2
E2, 16,16-Dimethylprostaglandin
Tree number(s): D10.251.355.255.550.775.450.300
D23.469.050.175.725.775.450.300
D23.469.700.660.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015064
Scope note: A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Ulcer Agents
Registry Number: M790V82VAC
CAS Type 1 Name: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11alpha,13E,15R)-
Previous Indexing: Prostaglandins (1966-1974)
Prostaglandins E (1975-1977)
Prostaglandins E, Synthetic (1978-1979)
Prostaglandins, Synthetic (1977)
Public MeSH Note: 91; was see under PROSTAGLANDINS E, SYNTHETIC 1980-90; DIMETHYLDINOPROSTONE & 16,16-DIMETHYLPROSTAGLANDIN E2 METHYL ESTER were see 16,16-DIMETHYLPROSTAGLANDIN E2 1980-93
Online Note: use 16,16-DIMETHYLPROSTAGLANDIN E2 to search DIMETHYLDINOPROSTONE & 16,16-DIMETHYLPROSTAGLANDIN E2 METHYL ESTER 1980-93
History Note: 91(80); was see under PROSTAGLANDINS E, SYNTHETIC 1980-90; DIMETHYLDINOPROSTONE & 16,16-DIMETHYLPROSTAGLANDIN E2 METHYL ESTER were see 16,16-DIMETHYLPROSTAGLANDIN E2 1980-93
Entry Version: DIMETHYLPGE2
DeCS ID: 4179
Unique ID: D015064
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1979/05/23
Revision Date: 2015/06/08
16,16-Dimethylprostaglandin E2 - Preferred
Concept UI M0023176
Scope note A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.
Preferred term 16,16-Dimethylprostaglandin E2
Entry term(s) 16,16 Dimethyl PGE2
16,16 Dimethylprostaglandin E2
16,16-Dimethyl-PGE2
E2, 16,16-Dimethylprostaglandin



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey