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Descriptor English: 2-Acetylaminofluorene
Descriptor Spanish: 2-Acetilaminofluoreno
Descriptor 2-acetilaminofluoreno
Entry term(s) 2-acetilamidofluoreno
2-fluorenilacetamida
Scope note: Hepatocarcinógeno cuyo mecanismo de acción implica la N-hidroxilación a ácido arilhidrosamínico, seguida de sulfonación enzimática a sulfoxifluorenilacetamida. Se emplea en el estudio de la carcinogenia y mutagenia de las aminas aromáticas.
Descriptor Portuguese: 2-Acetilaminofluoreno
Descriptor French: N-Fluorén-2-yl-acétamide
Entry term(s): 2 Acetamidofluorene
2 Acetylaminofluorene
2 Fluorenylacetamide
2-AAF
2-Acetamidofluorene
2-Fluorenylacetamide
AAF, Aminofluorene
Acetylaminofluorene
Aminofluorene AAF
Fluoren 2 ylacetamide
Fluoren-2-ylacetamide
N 2 Fluorenylacetamide
N Acetyl 2 Aminofluorene
N-2-Fluorenylacetamide
N-Acetyl-2-Aminofluorene
Tree number(s): D02.065.064.150
D02.241.081.018.110.080
D02.455.426.559.847.389.050
D04.615.389.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015073
Scope note: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Carcinogens
Registry Number: 9M98QLJ2DL
CAS Type 1 Name: Acetamide, N-9H-fluoren-2-yl-
Previous Indexing: Acetamides (1971-1974)
Fluorenes (1966-1974)
Public MeSH Note: 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Online Note: use 2-ACETYLAMINOFLUORENE to search ACETYLAMINOFLUORENE 1975-82
History Note: 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
DeCS ID: 115
Unique ID: D015073
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2013/07/08
2-Acetylaminofluorene - Preferred
Concept UI M0023186
Scope note A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Preferred term 2-Acetylaminofluorene
Entry term(s) 2 Acetamidofluorene
2 Acetylaminofluorene
2 Fluorenylacetamide
2-AAF
2-Acetamidofluorene
2-Fluorenylacetamide
AAF, Aminofluorene
Aminofluorene AAF
Fluoren 2 ylacetamide
Fluoren-2-ylacetamide
N 2 Fluorenylacetamide
N Acetyl 2 Aminofluorene
N-2-Fluorenylacetamide
N-Acetyl-2-Aminofluorene
Acetylaminofluorene - Broader
Concept UI M0023187
Preferred term Acetylaminofluorene



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