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Descriptor English: RNA Ligase (ATP)
Descriptor Spanish: ARN Ligasa (ATP)
Descriptor ARN ligasa (ATP)
Entry term(s) RNA ligasa (ATP)
polirribonucleótido sintetasa
Scope note: Enzima que cataliza la conversión del ARN lineal en una forma circular mediante la transferencia de 5'-fosfato al terminal 3'-hidroxilo. También cataliza la unión covalente de dos polirribonucleótidos en enlace fosfodiéster. EC 6.5.1.3.
Descriptor Portuguese: RNA Ligase (ATP)
Descriptor French: RNA ligase (ATP)
Entry term(s): Ligase, tRNA
Polyribonucleotide Synthetase
Synthetase, Polyribonucleotide
tRNA Ligase
Tree number(s): D08.811.464.754.720
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011130
Scope note: An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also catalyzes the covalent joining of two polyribonucleotides in phosphodiester linkage. EC 6.5.1.3.
Annotation: do not confuse entry term POLYRIBONUCLEOTIDE SYNTHETASE with entry terms POLYDEOXYRIBONUCLEOTIDE SYNTHETASES or POLYNUCLEOTIDE SYNTHETASES
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.5.1.3
CAS Type 1 Name: Poly(ribonucleotide):poly(ribonucleotide)ligase (AMP-forming)
Previous Indexing: Polynucleotide Synthetases (1974-1977)
Public MeSH Note: 98; see POLYRIBONUCLEOTIDE SYNTHETASE 1991-97; see POLYNUCLEOTIDE SYNTHETASES 1978-90
History Note: 98(78)
DeCS ID: 11567
Unique ID: D011130
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/05/23
Revision Date: 2005/07/27
RNA Ligase (ATP) - Preferred
Concept UI M0017244
Scope note An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also catalyzes the covalent joining of two polyribonucleotides in phosphodiester linkage. EC 6.5.1.3.
Preferred term RNA Ligase (ATP)
Entry term(s) Polyribonucleotide Synthetase
Synthetase, Polyribonucleotide
tRNA Ligase - Narrower
Concept UI M0017245
Preferred term tRNA Ligase
Entry term(s) Ligase, tRNA



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