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Descriptor English: DNA Ligases
Descriptor Spanish: ADN Ligasas
Descriptor ADN ligasas
Entry term(s) ADN-ligasa
DNA ligasas
polidesoxirribonucleótido ligasas
polidesoxirribonucleótido sintetasas
Scope note: Poli(desoxirribonucleótido):poli(desoxirribonucleótido)ligasas. Enzimas que catalizan la unión de desoxirribonucleótidos preformados en la unión fosfodiéster durante la reparación de una ruptura de una hebra en ADN bicatenario. La clase incluye tanto a EC 6.5.1.1. (ATP) como a EC 6.5.1.2. (NAD).
Descriptor Portuguese: DNA Ligases
Descriptor French: DNA ligases
Entry term(s): DNA Joinases
DNA Ligase
DNA Ligase, T4
Joinases, DNA
Ligase, DNA
Ligase, T4 DNA
Ligases, DNA
Ligases, Polydeoxyribonucleotide
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases
Synthetases, Polydeoxyribonucleotide
T4 DNA Ligase
Tree number(s): D08.811.074.500
D08.811.464.754.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011088
Scope note: Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
Annotation: do not confuse entry term POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with entry term POLYRIBONUCLEOTIDE SYNTHETASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.5.1.-
Previous Indexing: Polynucleotide Synthetases (1974-1977)
Public MeSH Note: 98; see POLYDEOXYRIBONUCLEOTIDE SYNTHETASES 1991-97, see POLYNUCLEOTIDE SYNTHETASES 1978-90; for DNA LIGASES see POLYNUCLEOTIDE SYNTHETASES 1974-77, & see DNA LIGASE 1973-76
History Note: 98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76
DeCS ID: 11522
Unique ID: D011088
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/05/23
Revision Date: 2020/05/27
DNA Ligases - Preferred
Concept UI M0017169
Scope note Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
Preferred term DNA Ligases
Entry term(s) DNA Joinases
DNA Ligase
Joinases, DNA
Ligase, DNA
Ligases, DNA
Ligases, Polydeoxyribonucleotide
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases
Synthetases, Polydeoxyribonucleotide
T4 DNA Ligase - Narrower
Concept UI M0017170
Preferred term T4 DNA Ligase
Entry term(s) DNA Ligase, T4
Ligase, T4 DNA



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