| Descriptor English: | Purpura, Thrombotic Thrombocytopenic | ||||||
| Descriptor Spanish: |
Púrpura Trombocitopénica Trombótica
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| Descriptor Portuguese: | Púrpura Trombocitopênica Trombótica | ||||||
| Descriptor French: | Purpura thrombotique thrombocytopénique | ||||||
| Entry term(s): |
Congenital Thrombotic Thrombocytopenic Purpura Familial Thrombotic Microangiopathy Familial Thrombotic Thrombocytopenia Purpura Familial Thrombotic Thrombocytopenic Purpura Microangiopathic Hemolytic Anemia, Congenital Microangiopathy, Familial Thrombotic Moschcowitz Disease Moschkowitz Disease Purpura, Thrombotic Thrombopenic Schulman Upshaw Syndrome Schulman-Upshaw Syndrome Thrombocytopenic Purpura, Thrombotic Thrombopenic Purpura, Thrombotic Thrombotic Microangiopathy, Familial Thrombotic Thrombocytopenic Purpura Thrombotic Thrombocytopenic Purpura, Congenital Thrombotic Thrombocytopenic Purpura, Familial Thrombotic Thrombopenic Purpura Upshaw Factor, Deficiency of Upshaw Schulman Syndrome Upshaw-Schulman Syndrome |
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| Tree number(s): |
C15.378.100.802.687.680 C15.378.140.855.925.750.680 C15.378.243.937.925.750.680 C15.378.925.850 C23.550.414.950.687.680 C23.888.885.687.687.680 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011697 | ||||||
| Scope note: | An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases. |
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| Allowable Qualifiers: |
BL blood CF cerebrospinal fluid CI chemically induced CL classification CN congenital CO complications DG diagnostic imaging DH diet therapy DI diagnosis DT drug therapy EC economics EH ethnology EM embryology EN enzymology EP epidemiology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PA pathology PC prevention & control PP physiopathology PS parasitology PX psychology RH rehabilitation RT radiotherapy SU surgery TH therapy UR urine VE veterinary VI virology |
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| Public MeSH Note: | 1986; see PURPURA, THROMBOTIC THROMBOPENIC 1965-1985 |
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| History Note: | 1986; use PURPURA, THROMBOTIC THROMBOPENIC 1965-1985 |
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| DeCS ID: | 12133 | ||||||
| Unique ID: | D011697 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1965/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2018/06/14 |
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Purpura, Thrombotic Thrombocytopenic
- Preferred
Congenital Thrombotic Thrombocytopenic Purpura
- Narrower
Familial Thrombotic Thrombocytopenic Purpura
- Narrower
| Concept UI |
M0018188 |
| Scope note | An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases. |
| Preferred term | Purpura, Thrombotic Thrombocytopenic |
| Entry term(s) |
Moschcowitz Disease Moschkowitz Disease Purpura, Thrombotic Thrombopenic Thrombocytopenic Purpura, Thrombotic Thrombopenic Purpura, Thrombotic Thrombotic Thrombocytopenic Purpura Thrombotic Thrombopenic Purpura |
| Concept UI |
M0500607 |
| Preferred term | Congenital Thrombotic Thrombocytopenic Purpura |
| Entry term(s) |
Familial Thrombotic Microangiopathy Microangiopathic Hemolytic Anemia, Congenital Microangiopathy, Familial Thrombotic Schulman Upshaw Syndrome Schulman-Upshaw Syndrome Thrombotic Microangiopathy, Familial Thrombotic Thrombocytopenic Purpura, Congenital Upshaw Factor, Deficiency of Upshaw Schulman Syndrome Upshaw-Schulman Syndrome |
| Concept UI |
M0500608 |
| Preferred term | Familial Thrombotic Thrombocytopenic Purpura |
| Entry term(s) |
Familial Thrombotic Thrombocytopenia Purpura Thrombotic Thrombocytopenic Purpura, Familial |
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