| Descriptor English: | Pyroglutamate Hydrolase | ||||||
| Descriptor Spanish: |
Piroglutamato Hidrolasa
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| Descriptor Portuguese: | Piroglutamato Hidrolase | ||||||
| Descriptor French: | 5-Oxoprolinase(ATP-hydrolysing) | ||||||
| Entry term(s): |
5 Oxoprolinase 5-Oxoprolinase Hydrolase, Pyroglutamate Oxoprolinase |
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| Tree number(s): |
D08.811.277.087.760 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011752 | ||||||
| Scope note: | Hydrolyzes pyroglutamic acid in the presence of ATP to glutamate plus ADP and inorganic phosphate. Deficiency leads to pyroglutamic acidurea. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.5.2.- | ||||||
| Previous Indexing: |
Amidohydrolases (1974) Pyrrolidonecarboxylic Acid (1974) |
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| Public MeSH Note: | 91; was see under AMIDOHYDROLASES 1975-90 |
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| History Note: | 91(75); was see under AMIDOHYDROLASES 1975-90 |
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| DeCS ID: | 12190 | ||||||
| Unique ID: | D011752 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1974/11/19 | ||||||
| Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Pyroglutamate Hydrolase
- Preferred
| Concept UI |
M0018271 |
| Scope note | Hydrolyzes pyroglutamic acid in the presence of ATP to glutamate plus ADP and inorganic phosphate. Deficiency leads to pyroglutamic acidurea. |
| Preferred term | Pyroglutamate Hydrolase |
| Entry term(s) |
5 Oxoprolinase 5-Oxoprolinase Hydrolase, Pyroglutamate Oxoprolinase |
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