| Descriptor English: | Dihydroorotase | ||||||
| Descriptor Spanish: |
Dihidroorotasa
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| Descriptor Portuguese: | Di-Hidro-Orotase | ||||||
| Descriptor French: | Dihydro-orotase | ||||||
| Entry term(s): |
Amidohydrolase, Dihydro-Orotate Carbamoylaspartic Dehydrase Dehydrase, Carbamoylaspartic Dihydro Orotase Dihydro Orotate Amidohydrolase Dihydro-Orotase Dihydro-Orotate Amidohydrolase |
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| Tree number(s): |
D08.811.277.087.280 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D004080 | ||||||
| Scope note: | An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro-orotic acid. EC 3.5.2.3. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.5.2.3 | ||||||
| CAS Type 1 Name: | (S)-Dihydroorotate amidohydrolase | ||||||
| Previous Indexing: |
Amidohydrolases (1966-1976) Orotic Acid (1966-1976) |
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| Public MeSH Note: | 95; was DIHYDRO-OROTASE 1977-94 (see under AMIDOHYDROLASES 1977-90) |
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| Online Note: | use DIHYDROOROTASE to search DIHYDRO-OROTASE 1977-94 |
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| History Note: | 95; was DIHYDRO-OROTASE 1977-94 (see under AMIDOHYDROLASES 1977-90) |
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| DeCS ID: | 4120 | ||||||
| Unique ID: | D004080 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1976/04/27 | ||||||
| Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Dihydroorotase
- Preferred
| Concept UI |
M0006391 |
| Scope note | An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro-orotic acid. EC 3.5.2.3. |
| Preferred term | Dihydroorotase |
| Entry term(s) |
Amidohydrolase, Dihydro-Orotate Carbamoylaspartic Dehydrase Dehydrase, Carbamoylaspartic Dihydro Orotase Dihydro Orotate Amidohydrolase Dihydro-Orotase Dihydro-Orotate Amidohydrolase |
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