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Descriptor English: beta-Lactamases
Descriptor Spanish: beta-Lactamasas
Descriptor beta-lactamasas
Scope note: Enzimas que se encuentran en muchas bacterias y catalizan la hidrólisis del enlace amídico en el anillo betalactámico. Las penicilinas y las cefalosporinas son conocidos antibióticos que son destruidos por estas enzimas.
Descriptor Portuguese: beta-Lactamases
Descriptor French: bêta-Lactamases
Entry term(s): beta Lactamase
beta Lactamases
beta-Lactamase
Tree number(s): D08.811.277.087.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001618
Scope note: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:beta-Lactamase Inhibitors
Registry Number: EC 3.5.2.6
CAS Type 1 Name: beta-Lactamhydrolase
Previous Indexing: Amidohydrolases (1966-1978)
Cephalosporinase (1975-1978)
Penicillinase (1966-1978)
Public MeSH Note: 79
History Note: 79
DeCS ID: 1639
Unique ID: D001618
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1979/01/01
Date of Entry: 1978/05/16
Revision Date: 2014/06/10
beta-Lactamases - Preferred
Concept UI M0002421
Scope note Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Preferred term beta-Lactamases
Entry term(s) beta Lactamase
beta Lactamases
beta-Lactamase



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